Case Western Reserve University

Steris Inc.

Other

Hathaway Brown School

Motorola Corporation

Rockwell Automation Technologies Incorporated

United States of America As Represented by the Administrator of Nasa

Reliance Electric Industrial Company

Chung-Chiun Liu

Laurie Dudik

Frederick Michael Discenzo

Paul S Malchesky

Jesse S Wainright

Tom L Merk

Michael A Centanni

Gregory J Hummer

Jinsong Yu

Henry G Hughes

Gary W Hunter

Robert F Savinell

Donald L Feke

Jennifer C Xu

Xi Shan

Joe H Payer

Kingman P Strohl

Cheng-Wei Liu

Seth Levine

Edward O'Connor

Dong Zhao

Po-Yuam Lin

Meijun Shao

Bonnie Gurry

Ann Lai

Metini Janyasupab

Yuan Zhang

Zhihong Jin

Laurie Ann Dudik

Xiaodong Wang

Vasilios A Karagounis

A sensor for the detection of an analyte in a biological sample includes a substrate, a working electrode and counter electrode formed on a surface of the substrate, and a receptor functionalized or chemically functionalized to a surface of an exposed portion of the working electrode. The receptor can selectively bind to the analyte of interest and the analyte once bound is detectable by measuring the current flow between the working electrode and counter electrode.

Electrochemical sensor for analyte detection

A detection system for determining pyruvate dehydrogenase (PDH) levels in a bodily sample includes at least one reaction solution for generating NADupon combination with PDH in the bodily sample, the reaction solution including pyruvate and NADH and a biosensor for determining the level of generated NAD.

System and method for detecting neural injury

A polymer electrolyte-based sensor is disclosed. The sensor includes a conductive polymer electrolyte film including water-retaining components. The water-retaining components facilitate operational conductivity of the conductive polymer electrolyte film in lower humidity environments than would be possible without the water-retaining components.

Polymer electrolyte-based sensors

A detection system for determining alpha-methylacyl-CoA (AMACR) levels in a bodily sample includes at least one reaction solution for generating HOupon combination with AMACR in the bodily sample and a biosensor for determining a level of generated HO. The reaction solution includes a (2R)-2-methylacyl-CoA epimer that can be chirally inverted by AMACR to a (2S)-2-methylacyl-CoA epimer and an enzyme that carries out beta oxidation with the (2S)-2-methylacyl-CoA epimer to generate hydrogen peroxide (HO).

System and method for detecting alpha-methylacyl-CoA racemase (AMACR) and prostate cancer

A detection system for determining lysyl oxidase-like 2 protein (LOXL2) levels in a bodily sample, includes at least one reaction solution for generating HOupon combination with LOXL2 in the bodily sample, the reaction solution including lysine that can be oxidatively deaminated by LOXL2 to generate &#x3b1;-aminoadipic-&#x3b4;-semialdehyde (allysine) and hydrogen peroxide (HO).

System and method for detecting lysyl oxidase-like 2 protein (LOXL2) and breast cancer

A detection system for an enclosed container for an enclosed cargo container includes a sensor device for sensing a material harmful to human beings within an enclosed cargo container and a detection device coupled to the sensor device for transmitting a corresponding signal to a monitoring device outside the cargo container. Containers which have harmful materials within them can be inspected or stopped before entering the country.

Sensor for container monitoring system

The invention is a flexible, micro-fabricated fuel cell and fuel cell stack that can be helically wound or bend into cylindrical shapes. The electrolyte is a proton exchange membrane (PEM) upon which can be printed, by ink jet means, the anode and cathode electrodes and the current collectors that convey current to or from the edges of the PEM which has a thickness on the order of 0.001 to 0.010 inch. Pluralities of the series connected fuel cell stacks can be arranged in electrical and physical parallel with one another to provide what are batteries of fuel cell stacks that can be connected by manifolds to sources of fuel and oxidizer. The invention is directed to a thin, light-weight, flexible fuel cell assembly that can be produced in ambient conditions using standard micro-fabrication techniques, such as thick film printing and ink jet deposition. Thick film printing techniques, screen printing or ink jet printing, are used to deposit porous current collectors on either side of the membrane.

Light-weight, flexible edge collected fuel cells

A system and method relating to in situ monitoring, analysis, and control of a lubricating material within a lubrication filter assembly is provided. A filter-sensor integration comprises a lubrication filter assembly and at least one lubrication sensing assembly, wherein the lubrication sensing assembly comprising at least one sensor array, and the sensor array comprises of at least one sensor. The lubrication filter assembly comprises a housing which defines a chamber, wherein lubricating material enters the chamber through a filter material. The lubrication sensing assembly is embedded into the chamber of the lubrication filter assembly, and the lubrication sensing device is positioned relative to the filter material so that the at least one sensor of the sensor array senses in situ different parameters of the lubricating fluid, analyzes measured parameters to determine health of the system, and generates a control signal to protect machinery and processes.

Filter integration for a lubrication analysis system

A hydrogen storage system is described that can fabricated under ambient atmospheric conditions and humidity. The hydrogen storage system includes hydrogen-absorbing alloy particles, such as AB-type alloys, for example LaNiAl, AB/AB-type alloys, for example MgNi, and AB-type alloys, and group VIII transition metal particles, such as Pd, Pt, Ni, Ru, and/or Re, that are mechanically alloyed. The mechanically alloyed particles are stable and retain their hydrogen-absorbing efficiency even after prolonged exposure to air and water. Binders and solvent can be added to produce low-viscosity inks. The hydrogen storage system can be used with fuel cells that can be microfabricated and optionally be integrated with electronic devices.

Microfabricated hydrogen storage device and metal hydride fuel cell/battery

A multichannel wireless telemetry system is disclosed. The system includes a transmitter and a receiver in communication with the transmitter. The transmitter includes a signal processing chip. The signal processing chip includes a plurality of input preamplifiers, a plurality of selective second amplifiers, a subcarrier oscillator connected to the selective second amplifiers, a timing circuit connected to the subcarrier oscillator, a calibration circuit connected to the timing circuit, and a 1-of-several decoder connected to the timing circuit. Each selective second amplifier is connected to a different input preamplifier.

Miniaturized multichannel transmitter and wireless telemetry system

A sensor for detecting hydrogen peroxide, comprising an element exhibiting piezoelectric properties having a metal-oxide-containing coating, the metal-oxide having a divalent or tetravalent state.

Sensor for determining concentration of fluid sterilant

A thick film electrochemical microsensor device for measuring or regulating chlorine and bromine in water, comprising a substrate to which is applied an optimum arrangement of at least two electrodes. The device is especially useful for measuring or regulating chlorine and bromine levels in swimming pool or spa water. A method of measuring or regulating ions of at least one of chlorine and bromine in water is also described, which comprises contacting the water with the microsensor of the present invention; measuring the current output of the microsensor; determining the level of at least one of chlorine and bromine indicated by the current output; and generating a signal.

Method for determining the amount of chlorine and bromine in water

A thick film electrochemical micro-sensor device for detecting or monitoring sulfur dioxide, comprising a substrate to which is applied a working electrode, a counter electrode, a reference electrode, and optionally a heater and a temperature detector, wherein a portion of the electrodes is covered with an insulator, and a portion of the electrodes is covered with an electrolyte. The device is especially useful for detecting or monitoring sulfur dioxide in emission gases. A method of detecting or monitoring sulfur dioxide emissions using the electrochemical micro-sensor device includes contacting the emission gas with the sensor of the present invention, measuring the current output of the sensor, determining if the current output indicates the presence of sulfur dioxide, and generating a signal, that can be used to actuate a scrubber system when a pre-determined level of sulfur dioxide is detected.

Method for detecting or monitoring sulfur dioxide with an electrochemical sensor

An electrolysis unit ( ) has an anode ( ) and a gas diffusion cathode ( ). Air is fed to the cathode ( ) to generate peroxide species, such as hydrogen peroxide, peroxide ions, or peroxide radicals by electrolysis of oxygenated water. A peracetic acid precursor, such as acetyl salicylic acid, reacts with the peroxide to form peracetic acid. An ion selective barrier ( ) optionally separates the unit into two chambers, an anodic chamber ( ) and a cathodic chamber ( ). By selecting either a proton permeable membrane or an anion exchange membrane for the barrier, the peracetic acid may be formed in either an alkaline electrolyte in the cathodic chamber or in an acid electrolyte in the anode chamber, respectively.

Electrolytic synthesis of peracetic acid

An electrolysis unit (,) has an ion selective barrier (,) for separating an anodic chamber (,) from a cathodic chamber (,). An electrolyte within the unit includes a precursor, such as potassium acetate, or acetic acid. A positive potential is applied to an anode (,) within the anodic chamber, resulting in the generation of a variety of shorter and longer lived oxidizing species, such as peracetic acid, hydrogen peroxide, and ozone. In one preferred embodiment, a solution containing the oxidizing species is transported to a site where articles, such as medical instruments, are to be decontaminated. The oxidizing species are generated as needed, avoiding the need to store hazardous decontaminants.

Growing community of inventors

Cleveland Heights, OH, United States of America

Chung-Chiun Liu