University of Chicago

Emd Millipore Corporation

Chunfang Zhao

David Aaron Schwartz

Stephen Joseph Kron

Amy Flor

Xinfang Zhao

Jimmy Williams

William B Busa

The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.

Methods and/or use of oligonucleotide conjugates for assays and flow cytometry detections

Growing community of inventors

San Diego, CA, United States of America

Chunfang Zhao