Leland Stanford Junior University

Other

Affymetrix, Inc.

Chunfai Lai

Quan Van Nguyen

Yunqing Ma

Garry P Nolan

Yury Goltsev

Shauna Levinson

Audrey Lin

Methods of assaying cells of a cellular sample for the presence of a target nucleic acid are provided. Aspects of the methods include evaluating a cellular sample that has been contacted with a nuclease inhibitor for the presence of a target nucleic acid. Also provided are devices and kits that find use in practicing the methods described herein.

Detection of target nucleic acids in a cellular sample

This invention provides compositions, methods, and systems for characterizing, resolving, and quantitating single stranded and double stranded DNA and RNA in-situ. Paired sense and anti-sense probes can signal the presence of double stranded nucleic acids. DNA and RNA can be distinguished in cell and tissue samples by hybridizing with probe sets adapted to highlight differences in these targets in-situ.

Detection of nucleic acids

Growing community of inventors

Fremont, CA, United States of America

Chunfai Lai