Other

National Yang Ming Chiao Tung University

Chun-Yuan Chang

Cheng-Han Tsai

Yun-Lian Lin

Yi-Jang Lee

Wei-Hsiang Hsu

Chung-Sheng Huang

Pin-Ho Lo

Bing-Ze Lin

Yuan-Heng Tu

The present invention provides an alcohol extract ofNakai ex Murata exhibits significant effects on inhibiting the senescence in human WI-38 lung fibroblasts and human dermal fibroblasts. Moreover, the alcohol extract ofis able to suppress the expression of the cofilin-1, a protein involved in actin dynamics and cell morphology and found to be increased in senescent cells. Suppression effect of cell senescence by this herb extract is more efficient in mild concentration without over-inhibition of cell viability and growth.

Method for treatment of cellular senescence

The invention provides a hole punch structure. More particularly, one end of an exposed longitudinal handle is moved together with a slide rod in a hole-punching mechanism covered by a casing. Thus, when the other end of the handle is pressed down, the slide rod is also moved transversely, a push rod connected to the slide rod is also moved, and a tool shelf is pressed vertically downward to achieve a hole-punching operation of a punching post. This hole punch structure works according to the principle of lever of the longitudinal handle.

Hole punch structure

The present invention provide a full folding/unfolding book stand and copy holder, which components are connected in one piece, so that it can be well connected when folding or unfolding; its strong triangular movable support components on the back can be adjusted for different angles when used, so that it is portable and convenience for use at various locations and thickness of books.

Full folding/unfolding book stand and copy holder

The present invention provides a dual protective device of a heavy-duty stapler, in particular to a control device of stapler that controls safely the action of striking slice with spring; of which, a base-controlled active protective device is mounted at rear side of the main body of the stapler, and operated in combination with a manually-operated safety switch that's arranged at front side of the main body of the stapler, thus forming an easy-to-use dual protective device.

Dual protective device of a heavy-duty stapler

A number lock device, comprising a lock housing, a lock core, a cable, a cover, a movable member, a driving member, a locking plate, and a locking pin. Thus, the number lock device can be operated by the user's one hand only, thereby facilitating the user operating the number lock device. In addition, the correct numbers of the number rings of the lock core of the number lock device can be changed easily and conveniently.

Number lock device for computer

A manually operated corner cutter includes a base, a support and guide device, a blade post, multiple cutting tools, a press and control handle, and a press plate. The support and guide device includes an upright support post and a slide seat each secured on the base. Thus, the manually operated corner cutter may be operated easily, rapidly and conveniently. In addition, the cutting tool may be replaced easily and conveniently, thereby facilitating replacement of the cutting tool.

Manually operated corner cutter

A quick holder includes a bottom housing, a cover, two clamping members, and a tensile spring. The tensile spring is urged between the retaining posts of the two clamping members conveniently, so that the two opposite clamping members may be used to clamp the paper by a single tensile spring, thereby simplifying the whole structure, and thereby decreasing the difficulty of assembly.

Quick holder

A security device is provided wherein spindle is engaged with a lock pin and the spindle is engaged with an abutment plate such that a locking/unlocking of the security device is effected by simply using one hand to rotate the spindle to cause the lock pin to rotate together. This device can inhibit the theft of small but expensive pieces such as a computer or the like.

Growing community of inventors

Taipei, Taiwan

Chun-Yuan Chang