Newbio Therapeutics, Inc.

Bestway Inflatables & Material Corp.

Mettler-toledo Gmbh

Mettler-toledo International Trading (shanghai) Co., Ltd.

Mettler Toledo Instrument (shanghai) Company Limited

Dell Products Inc.

Kao Corporation

Signify Holding B.v.

Semiconductor Manufacturing International (shanghai) Corporation

Philips Lighting Holding B.v.

Fudan University

Casco Signal Co., Ltd.

Mettler-toledo International Trading Co., Ltd.

Chun Yang

Nianhe Han

Deqiang An

Shuiyong Huang

Di Zeng

Chao Wu

Peng Fei Zhu

Naifeng Bian

Weixiang Sun

Hang Yang

Li Jian

Huali Li

Baoxiang Wang

Hans-Rudolf Burkhard

Feng Xu

Xiaobo Chen

Baohui Liu

Zhongxiong Zhu

Liang Chen

Gang Wang

Jing Xu

Chang Liu

Jie Fu

Zhi Quan Chen

Xianhui Zhang

Shan Shan Wang

Chris Chang Yu

Changde Wan

Shotaro Ito

Junhu Liu

Hiroshi Nojiri

Zhijun Ji

Ying Qi

Hang Chen

Xiaonan Liu

Ruiyuan Ye

Wan Zhang Qin

Fan Qi Kong

Mingzhen Li

Chengyu Hou

Liwei Song

Xiaolin Tang

Hand-Rudolf Burkhard

Disclosed herein is an anti-CD79b antibody or antigen-binding fragment thereof, a drug conjugate thereof and use thereof. The anti-CD79b antibody or antigen-binding fragment thereof herein comprises: HCDR1 comprising the amino acid sequence of SEQ ID NO: 1; HCDR2 comprising the amino acid sequence of SEQ ID NO: 2; HCDR3 comprising the amino acid sequence of SEQ ID NO: 3; LCDR1 comprising the amino acid sequence of SEQ ID NO: 4; LCDR2 comprising the amino acid sequence of SEQ ID NO: 5; and LCDR3 comprising the amino acid sequence of SEQ ID NO: 6.

Anti-CD79b antibodies, drug conjugates, and applications thereof

The present invention relates to a platform door control apparatus based on a double 2-vote-2 architecture, including a security communication and logic processing module, a driver collection module, and a maintenance module, the security communication and logic processing module is separately connected to the driver collection module and the maintenance module, and both the security communication and logic processing module and the driver collection module are devices using the double 2-vote-2 architecture. Compared with the prior art, the present invention has the following advantages of effectively improving linkage efficiency of a signal system and a platform door system, and the like.

Platform door control apparatus based on double 2-vote-2 architecture

A frame pool includes a pool body having a space for containing liquid and a support frame for supporting the pool body. The pool body has an upper edge with a sleeve. The support frame includes an upper frame extending through the sleeve and a plurality of support members holding the upper frame in an elevated position. The upper frame includes first upper tubes, second upper tubes, and connecting tubes connecting the first upper tubes to the second upper tubes. Collars are provided within assembling ends of the first and second upper tubes. Each end of each of the connecting tubes is movably inserted into a collar located within an assembling end of a corresponding one of the upper tubes. Anti-rust coatings on the outer surfaces of the connecting tubes can be prevented from being worn and water can be sealed out of the tubes of the upper frame.

Frame pool

The present invention is directed to tetramaleimide linkers and use thereof, more specifically to the compounds represented by formula I and their use in the preparation of antibody-drug conjugates (ADCs). The ADCs obtained from the tetramaleimide linkers have high homogeneity and stability, and could be used effectively for the treatment of various diseases including tumors. The definition of the groups in formula I is the same as that in the description. 

Tetramaleimide linkers and use thereof

A window for an above-ground pool is provided. The window includes a window portion () and a retainer bracket (). The window portion () includes a window pane () and a peripheral rim () around a perimeter of the window pane (). The peripheral rim () defines grooves () between inner and outer flanges () on opposite side of the peripheral rim (). The retainer bracket () includes a peripheral rim junction (), a peripheral plate () and a joint () connecting the peripheral rim junction () and the peripheral plate ().

Window for an above-ground pool

A weighing sensor is provided for an electronic balance. A weighing unit of the weighing sensor has a load-receiving portion, a fixing portion, and parallel guiding members that connect the load-receiving and fixing portions A lever, with a first end connected to the load-receiving portion, is located between the parallel guiding members and the fixing portion. A lower portion of a photoelectric position limiting block is connected to the fixing portion, and an upper portion thereof has a limiting structure. A tail end portion of a second end of the lever is disposed in the limiting structure, limiting its deviation. The photoelectric position limiting block has a photoelectric position sensor and a stop structure for limiting deviation of the tail end portion.

Weighing sensor and electronic balance having photoelectric position sensor with integrated stop structure

A weighing sensor and a lever are disclosed. The weighing sensor has a load-receiving portion, a fixing portion, and a parallel guiding portion connected to the load-receiving portion and the fixing portion. The parallel guiding portion has upper and lower parallel guiding units, separated from each other. The ends of the parallel guiding units are connected to the load-receiving portion and the fixing portion. The fixing portion has an extension located between the parallel guiding units. The extension is at a distance from both parallel guiding units and extends to the load-receiving portion. A gap is formed between the extension and the load-receiving portion; and the distance between the extension and the upper parallel guiding unit allows a lever to pass through. The weighing sensor has a simple structure, both the processing process and the assembly process are simplified, and the processing and assembly during production are facilitated.

Weighing sensor and lever

The present invention is directed to oxadiazole linkers and use thereof, more specifically to the compounds represented by formula I, II, and III, and their use in the preparation of antibody-drug conjugates (ADCs). The ADCs obtained from said oxadiazole linkers have high homogeneity and stability, and could be used effectively for the treatment of various diseases including tumors. The definition of the groups in formula I, II, and III is the same as that in the description. 

Oxadiazole linkers and use thereof

A joint assembly for a bracket pool. The joint assembly includes at least one receiving channel for receiving a supporting tube of the bracket pool. The joint assembly also includes an installation portion defining at least one coupling region. A detachable storage tray including a containing portion for storing objects and at least one connector is removably coupled to the at least one coupling region of the installation portion for removably connecting the detachable storage tray the installation portion. The detachable storage tray is very convenient to install and disassemble, very stable in use, does not occupy extra space, and has low economic costs and manufacturing time and costs.

Bracket pool with a detachable storage tray

An above ground pool assembly comprises a bracket and a pool body. The bracket includes a plurality of horizontal and vertical support members. The horizontal support members couple to one another forming an upper frame. The plurality of vertical support members couple to the upper frame. The pool body has a side wall, wherein a top of the side wall is provided with a plurality of sleeves. The sleeves attach to the plurality of horizontal support members. Each horizontal support member has an outer surface with an uneven texture. The uneven texture reduces the contact areas between the pool body and the horizontal support members and avoids adhesion between the pool body and the horizontal support members, so that the pool body and the bracket can be separated easily, thereby reducing the possibility of damaging the pool body. Moreover, the wear resistance and slip resistance of the bracket are improved.

Above ground pool assembly

Disclosed are a type of tridentate linkers and use thereof. The tridentate linkers can be used to prepare an antibody drug conjugates as represented by formula I,L-(T-A-D)&#x2003;&#x2003;Iwherein, L is an antibody, antibody fragment or protein; T is a tridentate linker part; A is a cleavable linker group or a noncleavable linker part; D is a drug part; n is an integer of 0-8. The structure of the tridentate linker part is as represented by formula II, wherein, W is substituted aryl, heteroaryl, linear alkyl, cycloalkyl, heterocycloalkyl, or any combination thereof.

Tridentate connexon and use thereof

The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of, and, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting ofand, or an extract thereof as an active ingredient.

Ceramide production-accelerating agent

A load cell is provided with protection against damage from overload. The load cell has a load receiving member, a main member and a load transmitting member. The main member has a movable portion, a fixed portion and a first parallel guiding member for connecting the fixed portion and the movable portion. The load transmitting member has a first mounting portion for mounting the load receiving member, a second mounting portion for mounting the movable portion and a parallel guiding member for connecting the first mounting portion to the second mounting portion. The first mounting portion is movable vertically relative to the second mounting portion when a load being applied on the first mounting portion. The load-transmitting member is a single piece. The load cell also has a stop portion for preventing the first mounting portion from further moving downwardly for overload protection.

Load cell with streamlined structure and overload protection

Derivatives of dolastatin 10 and uses thereof, the structures of which are shown as formula I, II, III and IV are provided. 

Derivatives of dolastatin 10 and uses thereof

Growing community of inventors

Shanghai, China

Chun Yang