Purzer Pharmaceutical Co., Ltd.

National Research Institute of Chinese Medicine, Ministry of Health and Welfare

Chun-Tang Chiou

Ji-Wang Chern

Keng-Chang Tsai

Pei-Teh Chang

Yi-Chia Huang

Chia-Ching Liao

Wen-Chi Wei

Grace Shiahuy Chen

Chiung Hua Huang

Chien-Jung Lin

Wen-Hui Chiou

Jui-Shan Lin

Hsueh-Yun Lee

Kuan-Yu Chen

Yi-Chang Su

Yao-Haur Kuo

Kuo-Ming Yeh

Meng-Ling Chen

A composition of plant ingredients, a herbal composition for inhibiting coronavirus and cytokine storm, and a preparation method of the herbal composition are introduced. The composition of plant ingredients has Heartleaf Houttuynia, Indigowoad Root, Fineleaf Nepeta, Saposhnikovia Root, Mulberry Leaf, Scutellaria Root, Mongolian Snakegourd Fruit, Magnolia Bark, Peppermint Herb and Baked Liquorice Root. The herbal composition has 1 to 20 parts by weight of Heartleaf Houttuynia, Indigowoad Root, Fineleaf Nepeta, Saposhnikovia Root, Mulberry Leaf, Scutellaria Root, Mongolian Snakegourd Fruit, Magnolia Bark, Peppermint Herb and Baked Liquorice Root. The preparation method contains providing Heartleaf Houttuynia, Indigowoad Root, Fineleaf Nepeta, Saposhnikovia Root, Mulberry Leaf, Scutellaria Root, Mongolian Snakegourd Fruit, Magnolia Bark, Peppermint Herb and Baked Liquorice Root; and soaking all the herbs described above in water and boiling the water to prepare a herbal liquid, the volume of which is about one-third of an initial volume of the water.

Composition of plant ingredients, herbal composition and preparation method of the herbal composition

The present invention is related to derivatives of benzenesulfonamide represented by formula (I), and the pharmaceutical composition thereof. In addition, the benzenesulfonamide derivatives disclosed in the present invention can serve as potential cell cycle inhibitors, and thereby these benzenesulfonamide derivatives and the pharmaceutical composition thereof can be antitumor drug candidates, which might aim at cell cycle. Particularly, the benzenesulfonamide derivatives disclosed in the present invention may function as antitumor drugs to treat solid cancers. 

Benzenesulfonamide derivatives and pharmaceutical composition thereof

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Taipei, Taiwan

Chun-Tang Chiou