The Uab Research Foundation

Altimmune, Inc.

Chun-Ming Huang

De-Chu C Tang

Elias Meezan

Dennis J Pillion

JianFeng Zhang

John Jefferson Arnold

The present invention relates to the decontamination of anthrax spores, prophylaxis and treatment of anthrax infections and, more particularly, to compounds that act as specific inhibitors ofgermination/outgrowth-associated proteins, methods and means for making such inhibitors and their use as pharmaceuticals and/or vaccines. The invention also relates to the prophylaxis and treatment of anthrax infections and, more particularly, to vaccines and compositions that compriseantigens, epitopes, proteins, or nucleic acid molecules, including anthrax protective antigen, anthrax lethal factor, anthrax edema factor and anthrax proteins associated with spore germination and outgrowth, as well as methods and means for making such compositions and their use pharmaceuticals and/or vaccines.

Targets and compositions for use in decontamination, immunoprophylaxis, and post-exposure therapy against anthrax

Described herein are methods for the noninvasive immunization of a subject that involve alkyl glycosides. Also described herein are compositions, kits, and devices for the noninvasive immunization of a subject.

Alkyl-glycoside enhanced vaccination

Growing community of inventors

Gaithersburg, MD, United States of America

Chun-Ming Huang