Daewoong Pharmaceutical Co., Ltd.

Seoul National University

Yuhan Corporation

Dong-a Pharmaceutical Co., Ltd

Chun Ho Lee

Deok Ki Eom

Hyo-Soo Kim

Ja Kyung Yoo

Yeon Im Lee

Ji Sung Yoon

Myunggi Jung

Nora Lee

Jun Hee Lee

Ji Duck Kim

Jong Wook Lee

Tae Dong Han

Seung Chul Lee

Sun Ah Jun

Mi Ryeong Han

Kyung A Yu

Jeong-Taek Shin

Bong Yong Lee

Jae Sung Yang

Joong In Lim

Jeong-Hyun Son

Hyo Shin Kim

Ha Nee Seo

Eun Ji Koh

Il-Hwan Kim

Moon Ho Son

Hyung-Geun Lee

Yun Hur

Hyun Kyoung Ko

Jae Young Shim

Mi Kyung Kim

Sung-Young Kim

Suk Won Yun

Hye Ryun Shin

The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases. 

Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same

The present invention relates to a method for preparing intermediates of 4-methoxypyrrole derivatives. The preparation method according to the present invention has advantages that a high-temperature reaction is not required as a whole, inexpensive and non-explosive reagents are used instead of (trimethylsilyl)diazomethane, and further an intermediate of 4-methoxy pyrrole derivatives can be prepared as a whole at a high yield.

Method for preparing intermediate of 4-methoxypyrrole derivative

The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases.

3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same

The invention relates to a compound represented by Chemical Formula 1, below, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the compound or salt. The compound of the invention or pharmaceutically acceptable salts thereof can be used for the prevention or treatment of sodium channel blocker-related diseases. 

Substituted benzenesulfonamides as sodium channel blockers

The present invention provides a 4-methoxy pyrrole derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition containing the same. The 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof according to the present invention have not only excellent proton pump inhibitory activity, gastric damage-inhibiting activity and defensive factor-enhancing effects, but also excellent eradication activity against. Therefore, the 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof can be effectively used for the prevention and treatment of gastrointestinal damage due to gastrointestinal tract ulcer, gastritis, reflux esophagitis or. Moreover, the 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof, have inhibitory activities against GPCR and thus can be effectively used for the prevention and treatment of 5-HT receptor-mediated or muscarinic acetylcholine receptor-mediated diseases.

4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same

Disclosed are a sulfonylindole derivative useful for the prevention or treatment of peptic ulcer, gastritis or reflux esophagitis, a method of preparing the same, and a pharmaceutical composition containing the same.

Sulfonylindole derivatives and method for preparing the same

Provided are 1-phenylpiperidin-3-one derivatives and pharmaceutically acceptable salts thereof, having cysteine protease inhibitory activity, pharmaceutical compositions containing the same as an active ingredient, and processes for the preparation thereof.

1-phenylpiperidin-3-one derivatives and processes for the preparation thereof

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Seoul, South Korea

Chun Ho Lee