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Chonnam National University

Chul Ho Yun

Dong Hyun Kim

Geun Joong Kim

Dae Eun Cheong

Keon Hee Kim

Su Kyoung Yoo

Hye Ji Choi

Thien Kim Le

Sun Ha Park

Ji Yeon Kang

A recombinant vector according to an embodiment of the present invention may be used for producing a reconstituted cytochrome P450 oxygenase-reductase fusion protein. Oxygenase and reductase may be independently expressed in a host cell into which the recombinant vector is introduced, and then may be fused with a split intein so that it is possible to increase the heme content contained in the active site of the oxygenase and improve enzyme activity and stability.

Recombinant vector and method for producing reconstituted cytochrome P450 oxygenase-reductase fusion protein using the same

A method of producing human metabolites of simvastatin or lovastatin, and more particularly, a method of producing human metabolites of simvastatin and lovastatin by using bacterial cytochrome P450 BM3(CYP102A1) or mutants thereof, and a composition and kit therefor.

Preparation method of human metabolites of simvastatin or lovastatin using bacterial cytochrome P450 and composition therefor

Provided is a method of preparing piceatannol, and more particularly, to a method of preparing piceatannol from resveratrol using bacterial cytochrome P450 BM3 (CYP102A1) or mutants thereof, and a composition and a kit therefor.

Method of preparing piceatannol using bacterial cytochrome P450 and composition therefor

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Daejeon, South Korea

Chul Ho Yun