Korea Research Institute of Bioscience and Biotechnology

Bioland Ltd.

Activon Co., Ltd.

Chul Ho Kim

Jeong-Woo Seo

Baek Rock Oh

Jung Hyun Ju

Hack Sun Choi

Sun-Yeon Heo

Sun Yeon Heo

Jeong Woo Seo

Jong Jae Yi

Young Bae Kim

Jong Hyun Kim

Ki Ho Kim

Mi Jin Kim

Hyun Jin Kim

Sang Ki Rhee

Bong Hyun Sung

Sung Mok Lee

Jung Hoon Sohn

Lianhua Luo

Kwang Mook Lim

Soo Nam Park

Dina Rairakhwada

Jang Min Park

Kang Ll Ko

Sang Min Lee

Won Kyung Hong

You Ree Jung

Ji Hun Seomoon

The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.

Method for producing multi-hydroxy derivatives of polyunsaturated fatty acids

CH53 strain has high productivity of 1,3-propanediol from glycerol and uses thereof. It is confirmed thatCH53 strain is capable of converting at very high yield glycerol or crude glycerol to high-concentration 1,3-propanediol. SinceCH53 strain of the present invention capable of producing large amounts of 1,3-propanediol is one kind of lactic acid bacteria that are safe for humans (GRAS, Generally Recognized As Safe), when it is used for producing 1,3-propanediol from crude glycerol, it would be very advantageously used, unlike existing GMO strains, in related industries from the viewpoint of safety or environment and also providing an advantage of recycled use of resources.

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The present invention relates to a method for producing 1,3-propanediol using a mutant microorganism lacking a 2,3-butanediol synthetic gene, and more particularly to a mutant microorganism wherein a gene encoding lactate dehydrogenase and a gene encoding an enzyme which is involved in 2,3-butanediol synthesis are deleted in a microorganism having the ability to produce 1,3-propanediol from glycerol and wherein a gene encoding pyruvate decarboxylase and a gene encoding aldehyde dehydrogenase are introduced or amplified, and to a method of promoting the production of 1,3-propanediol while inhibiting the production of 2,3-butanediol by using the mutant microorganism. The use of the glycerol-fermenting mutant microorganism according to the present invention can significantly increase the production of 1,3-propanediol while minimizing the production of 2,3-butanediol.

Method for producing 1,3-propanediol using microorganism variant with deletion of 2,3-butanediol synthetic gene

The present invention relates to beta-glucosidase that is mutated to have enhanced activity, and a method for producing bioethanol using the same. More particularly, the present invention relates to a polynucleotide encoding beta-glucosidase that is mutated to have enhanced activity, beta-glucosidase expressed from the polynucleotide, an expression vector including the polynucleotide, a transformant that is transformed with the expression vector, a method for producing the mutated beta-glucosidase using the transformant, and a method for producing bioethanol using the transformant. The mutant beta-glucosidase of the present invention increases production of glucose much more than the conventional beta-glucosidase, and thus it can be widely used for economic production of bioethanol.

Mutant beta-glucosidases having enhanced activity and a method for producing bioethanol using the same

The present invention relates to a method for producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by inserting or amplifying a gene encoding propanediol utilization protein in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source. According to the present invention, 3-hydroxypropionic acid can be produced in high yield from glycerol without having to add expensive coenzyme B12 as a cofactor.

Method for preparing 3-hydroxypropionic acid from glycerol in high yield

The present invention relates to novel thraustochytrid-like microalgae having the ability to produce bio-oil, and a method of producing bio-oil using the same. The microalgae of the invention accumulate bio-oil at a high ratio in the cells when being cultured in glucose-containing medium, and thus can produce bio-oil in a high yield. Also, the microalgae can produce bio-oil using bean powder as a nitrogen source, and a product obtained by culturing edible bean powder as medium can be used as a raw material for producing food and feed. Also, the microalgae can produce bio-oil using non-food cellulosic biomass as a carbon source. Moreover, the use of non-food cellulosic biomass for production of bio-oil can overcome the factors limiting the development of bio-oil, including the unstable supply of food resources and an increase in the cost of raw materials, and can improve the commercial competitiveness of microbial fermentation oil.

Thraustochytrid-based microalgae, and method for preparing bio-oil by using same

The present invention is related to novel cosmetic composition comprising beta-fructosyl-L-ascorbic acid derivatives produced by fructose conversion reaction using by ascorbic acidskin whitening cosmetic composition as an cream, skin, lotion, pack and the like.

Cosmetic composition comprising beta-fructosyl-L-ascorbic acid for skin whitening

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Daejeon, South Korea

Chul Ho Kim