Other

Juridical Foundation the Chemo-sero-therapeutic Research Institute

Mitsui Toatus Chemical, Inc.

Ajinomoto Co., Ltd.

Kurita Water Industries Ltd.

Kohjin Co., Ltd.

Shinkohjinkasei Co., Ltd.

Hirayama, Chuichi

Chuichi Hirayama

Hirotaka Ihara

Sunao Morimoto

Keijun Hiraoka

Yoshiaki Motozato

Junichi Ida

Masao Honma

Katsutoshi Aihara

Takenori Hirai

Shunsei Tsunoda

Haruo Fuzita

Kazufumi Yagyu

Munehiro Saisho

An insoluble material for adsorbing a pyrogen comprising a polymer of an aziridine compound. According to the present invention, a large amount of the pyrogen can be easily removed from a solution containing pyrogen, and a large amount of the material for adsorbing the pyrogen can be prepared in easy steps. Therefore, the adsorbing material can greatly contribute to the preparation of medicines.

Material for adsorbing pyrogen

An insoluble material for adsorbing a pyrogen comprising a polymer of an aziridine compound. According to the present invention, a large mount of the pyrogen can be easily removed from a solution containing pyrogen, and a large amount of the material for adsporbing the pyrogen can be prepared in easy steps. Therefore, the adsorbing material can greatly contribute to the preparation of medicines.

Method of adsorbing pyrogens

Here is disclosed a water-insoluble pyrogen adsorbent composed of a polymer possessing amide groups optionally modified, said polymer being, e.g., a poly amino acid, a nylon, on a polyacrylamide.

Pyrogen adsorbent containing amide groups

An artificial carrier particle comprising an anionic polymer and a synthetic polyamino acid having at least one carboxylic group and at least one amino group in its side chain, the complex being insolubilized by an aldehyde crosslinking agent. The artificial carrier particle is useful in immunoassay, in particular, particle immunoassay. The artificial carrier particles are obtained by preparing an aqueous solution containing an anionic polymer and a synthetic polyamino acid comprising at least one free carboxyl group and at least one free amino group in its side chain, adjusting the pH of the solution to 3.5 to 9.5 at room temperature or at progressively increasing temperature under stirring to form solution particles of a desired particle size, and insolubilizing the particles by an aldehyde crosslinking agent.

Artificial carrier particles and method for preparation thereof

A method for preparing granular porous chitosan which comprises dispersing an acidic aqueous solution of chitosan in a hydrophobic dispersing medium; and, evaporating water off while stirring the resulting dispersion.

Method for preparing granular porous chitosan

The present invention provides novel spherical grains of polyamino acid wh can be used as a filler in chromatography, cosmetic powder and the like. The spherical grains can be produced by a method which comprises the steps of preparing a solution of hydrophobic polyamino acid such as poly n-leucine dissolved in an organic solvent; adding the solution to an aqueous medium and agitating said medium so as to obtain a dispersion of the spherical grains of the polyamino acid dispersed in the aqueous medium while evaporating the organic solvent; and taking out the spherical grains of polyamino acid from the dispersion.

Spherical grains of polyamino acid and production method thereof

Growing community of inventors

Kumamoto-ken, Japan

Chuichi Hirayama