Chang Gung University

Chuan-Tien Hung

Shin-Ru Shih

Yu-An Kung

Sheng-Yu Huang

Peng-Nien Huang

Yu-Nong Gong

Huan-Jung Chiang

Hsin-Ping Chiu

Chiung-Guei Huang

Disclosed herein is a method for inhibiting virus infection, including administering to a subject in need thereof an effective amount of a ferroptosis inhibitor or a pharmaceutically acceptable salt thereof. Also disclosed is a method for inhibiting viral replication, including contacting a virus with a ferroptosis inhibitor or a pharmaceutically acceptable salt thereof.

Method for inhibiting virus infection and replication

Disclosed herein are recombinant polypeptides derived from FBP1 and FBP2. Also disclosed herein are recombinant expression vectors and recombinant host cells for producing the aforesaid recombinant polypeptides. The recombinant polypeptides are proven to be useful and effective in producing a picornavirus with a type I internal ribosome entry site (IRES), so as to facilitate the preparation of a viral vaccine.

Recombinant polypeptides derived from FBP1 and FBP2 and uses of the same

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Taichung, Taiwan

Chuan-Tien Hung