Baxter International Inc.

Chuan Qin

Lecon Woo

Michael T K Ling

Patrick T Ryan

Yuanpang Samuel Ding

Birendra K Lal

Yuan-pang Samuel Ding

Donna L Rostron

Susan R Mizener

Michael T Ling

Sherwin S Shang

Tahua Yang

Sarah Louise Corbin

Martin F Miller

Richard Mennenoh

George Dillon

Dale Pennington

Dean G Laurin

Barrett E Rabinow

Samuel Ding

Chi J Chen

Jerry Ripley

Leoon Woo

Daniel Beedon

Biran Lal

Birenda K Lal

John O'Connor

Michael K Oberhaus

A polymer blend for fabricating medical products having a first 1,2 polybutadiene present from about 1% to about 99% by weight of the blend and having a first melting point temperature; and a second 1,2 polybutadiene present from about 1% to about 99% by weight of the blend and having a second melting point temperature higher than the first melting point temperature.

Method and process for enhancing properties and medical tubing performance in a polybutadiene material

The present invention provides a method for assembling a medical device using solvent bonding techniques. The method includes the steps of: (1) providing a first article of a polymer composition having (a) a first component of a homopolymer or copolymer obtained using monomers of cyclic olefin or a bridged polycyclic hydrocarbon, the first component being present in an amount from about 30% to about 100% by weight of the composition and (b) a second component from 0-70% by weight of the composition; (2) providing a second article of a material selected from the group of low crystallinity polymers; (3) applying a solvent to one of the first article or the second article to define an interface area; and (4) bonding the first article to the second article along the interface area.

Method for solvent bonding polyolefins

The present invention provides a method for using a polymeric cement to assemble medical devices. The method includes the steps of: (1) providing a first article of a low crystallinity polymer; (2) providing a second article of a low crystallinity polymer; (3) providing a cement composition having a first component of a cyclic olefin containing polymer or a bridged polycyclic hydrocarbon containing polymer and a second component of an effective amount of a solvent having a solubility parameter of less than about 20 (MPa) ; applying the cement composition to one of the first and second articles to define a bonding area; and (4) attaching the first article to the second article along the bonding area to fixedly attach the first article to the second article.

Solvent bonding method for polyolefin materials

The present invention provides a polymer composition having: a first component selected from homopolymers and copolymers of cyclic olefin containing polymers and bridged polycyclic hydrocarbon containing polymers, the first component being present in an amount from about 1-99% by weight of the composition; and a second component is selected from homopolymers and copolymers of a diene having from 4 to 12 carbons, the second component being present in an amount from about 99% to about 1% by weight of the composition.

Cycloolefin blends and method for solvent bonding polyolefins

The present invention provides a method for fabricating a medical tubing. The method includes the steps of: (1) providing a material selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the ethylene copolymers are obtained by copolymerizing ethylene with a comonomer selected from the group consisting of lower alkyl olefins, lower alkyl esters of a carboxylic acid and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene each have from 3-18 carbons, or blends thereof; (2) providing an extruder with an extrusion die; (3) extruding the material into a medical tubing; (4) providing a surface modifier solution; (5) preheating the surface modifier solution to a temperature within the range of 50-80&deg; C.; and (6) applying the preheated solution onto the tubing at it exits the extrusion die when the tubing is in a molten state or a semi-molten state.

Method of surface modifying a medical tubing

The present invention provides a method for using medical tubing for infusing therapeutic fluids to a patient comprising the steps of: providing a medical tubing having a sidewall of a polymeric blend, the blend having a polymeric material in an amount by weight within the range of 99.999%-90.0%, and an additive in an amount by weight within the range of 0.001%-10%, the tubing having been oriented along a longitudinal axis of the tubing to define a oriented diameter that is less than a diameter of the tubing before orienting; and providing fluid under pressure through the tubing to the patient.

Method of using medical tubings in fluid administration sets

A protein-compatible polymer blend made from a water-soluble polymer and a matrix polymer. The glass transition temperature of either the water-soluble polymer or the matrix polymer is greater than the application temperature, i.e., the temperature at which the protein-compatible polymer blend is being used.

Biomaterials with hydrophilic surfaces

The present invention provides a medical device of a polymer composition. The composition has a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

The present invention provides a polymer composition having a first component obtained by copolymerizing a norbornene monomer and an ethylene monomer, the first component being in an amount from about 1-99% by weight of the composition; and a second component of an ethylene and &agr;-olefin copolymer, the &agr;-olefin having 6 carbons, the second component being in an amount from about 99% to about 1% by weight of the composition.

The present invention provides a method of using a medical tubing with a pump for administering measured amounts of a beneficial fluid over time to a patient comprising the steps of providing a tubing having a first layer selected from the group consisting of ethylene homopolymers and ethylene copolymers, wherein the copolymers of ethylene are an ethylene monomer copolymerized with at least one monomer selected from the group consisting of lower alkyl olefins, lower alkyl esters of a carboxylic acid, and lower alkene esters of a carboxylic acid, the lower alkyl and lower alkene having from 3 to 18 carbons, the tubing having been exposed to a sterilization dosage of radiation of from about 15 to about 45 kGys; and pumping fluid through the tubing with the pump.

Medical tubing and pump performance enhancement by ionizing radiation during sterilization

The present invention provides a method for fabricating flexible medical tubings comprising the steps of providing a tubing of a polymer material, the tubing having a longitudinal axis and an initial diameter, orienting the tubing along the longitudinal axis of the tubing to reduce the diameter of the tubing to define a oriented diameter, and applying heat to the oriented tubing to heat set the tubing to maintain dimensional stability of the tubing over a temperature to which the tubing will normally be exposed.

Heat setting of medical tubings

The present invention provides a polymeric blend suitable for adhesive bonding to polar polymeric materials comprising an ultra-low density polyethylene in an amount by weight within the range of 99.999%-90.0%; and an additive selected from the group consisting of polyoxyethylene(5)oleylamine, bis(2-hydroxyethyl)soyaamine, bis(2-hydroxyethyl)oleylamine, and polyoxyethylene(5)octadecylamine, the additive in an amount by weight within the range of 0.001%-10%.

Surface modified polymeric material formulation

A polymeric tubing having an initial diameter and suitable for connecting to rigid housings including a sidewall defining a fluid pathway and having a longitudinal axis, the sidewall of a polymeric material in an amount by weight within the range of 99.999%-90.0%, and an additive in an amount by weight within the range of 0.001%-10%, and wherein the tubing has been oriented along its longitudinal axis to decrease its diameter to define a oriented diameter.

Oriented medical tubing

A device, a system and a method are provided for controllably releasing a product (26) into a container (10) in which the product (26) is mixed with another product contained within an interior (14) of the container 10. The device (12) releases the product (26) due to variations in temperature or pressure that the system experiences during an autoclaving or sterilization procedure, for example. Materials and shapes of the members (20, 20a, 20b, 22) of the device (12) are selected such that the members (20, 20a, 20b, 22) react or otherwise move within the device in a predetermined manner in response to changes in temperature or pressure. As a result, products (26) within the device (12) may be maintained separately from products within the interior (14) of the container (10) in which the device (12) is held. Prior to administration of a solution within the container (10), the product (26) within the device (12) may be mixed with the solution or other product in the container (10) in a controllable fashion.

System, method and device for controllably releasing a product

The present invention provides a method for fabricating flexible medical tubings including the steps of providing a polymeric material, forming a tubing from the polymeric material, the tubing having a longitudinal axis and an initial diameter, and orienting the tubing along the longitudinal axis of the tubing to reduce the diameter of the tubing to define an oriented diameter.

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Gurnee, IL, United States of America

Chuan Qin