Sony Corporation

Novozymes A/s

The Scripps Research Institute

Baidu Online Network Technology (beijing) Co., Ltd.

Sony Mobile Communications Inc.

Shanghai Xiaodu Technology Co. Ltd.

Chu Wang

Yan Wang

Na Wei

Lisbeth Kalum

Lars Henrik Oestergaard

Benjamin F Cravatt

Ben Xu

Jian Xie

Yucheng Zhou

Wensong He

Yafei Miao

Wenqi Huang

Keriann M Backus

Yongyi Liu

Wenbo Xu

Jinpeng Zhang

Yipin Zhang

Lars Henrik ØStergaard

Embodiments of the present disclosure provide a method and apparatus for outputting information. A specific embodiment of the method includes: in response to receiving a query, detecting whether there is an entity slot in the query; in response to there being an entity slot in the query, adding the detected entity slot to a candidate slot; detecting, in the query, a relationship-determinative word of an entity; searching in a preset knowledge graph for a peripheral knowledge graph of the candidate slot; and inferring on the basis of the peripheral knowledge graph according to the relationship-determinative word, and outputting an entity word matching the relationship-determinative word.

Method and apparatus for outputting information

Cells produce electrophilic products with the potential to modify and affect the function of proteins. Chemoproteomic methods have provided a means to qualitatively inventory proteins targeted by endogenous electrophiles; however, ascertaining the potency and specificity of these reactions to identify the most sensitive sites in the proteome to electrophilic modification requires more quantitative methods. Here, we describe a competitive activity-based profiling method for quantifying the reactivity of electrophilic compounds against 1000+ cysteines in parallel in the human proteome. Using this approach, we identify a select set of proteins that constitute hot spots for modification by various lipid-derived electrophiles, including the oxidative stress product 4-hydroxnonenal (HNE). We show that one of these proteins, ZAK kinase, is labeled by HNE on a conserved, active site-proximal cysteine, resulting in enzyme inhibition to create a negative feedback mechanism that can suppress the activation of JNK pathways by oxidative stress.

Cysteine-reactive ligand discovery in proteomes

A user equipment is operative to receive prioritization information for a plurality of unlicensed carriers from a cellular network node and to use the prioritization information for channel measurements or carrier selection.

User equipment, cellular network node and method for providing licensed-assisted access

The use of a peroxidase, a source of hydrogen peroxide and a mediator for providing a modified color in the textile is described.

Color modification of textile

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Beijing, China

Chu Wang