Merck Patent Gmbh

Boehringer Mannheim Gmbh

Merck Patent Gesellschaft MIT Beschrankter Haftung

Other

Roche Diagnostics Gmbh

Merck Patent Gesellschaft

Christos Tsaklakidis

Dieter Dorsch

Werner Mederski

Bertram Cezanne

Johannes Gleitz

Markus Klein

Lars Thore Burgdorf

Wolfgang Staehle

Birgitta Leuthner

Christopher Barnes

Paul Czodrowski

Norbert Beier

Angelika Esswein

Rolf Gericke

Herbert Leinert

Christina Esdar

Margarita Wucherer-Plietker

Frieder Bauss

Elmar Bosies

Gerd Zimmermann

Christoph Van Amsterdam

Mathilde Muzerelle

Hanns Wurziger

Gisbert Sponer

Thomas Fuchss

Horst Juraszyk

Hans Guehring

Dirk Wienke

Peter Freund

Liesel Dorge

Wolfgang Schafer

Brigitta Leuthner

Wolfgang Schaefer

Walter-Gunar Friebe

Klaus Kaluza

Alfred Mertens

Hans-Willi Krell

Konrad Honold

Dieter Herrmann

Ulrich Martin

Richard Engh

Ansgar Wegener

Manja Friese-Hamim

Wulf Pahlke

Rainer Haag

Michael Schultz

Silvia Konetschny-Rapp

Frank Czauderna

Johannes Gleiltz

Christopher Bames

Wrner Mederski

Compounds of the formula Ia and Ib in which R, Rand Rhave the meanings indicated in claim, are inhibitors of ATR, and can be employed for the treatment of diseases such as cancer.

5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives

Compounds of the formula I in which X, X, X, X, R, R, R, Q and Y have the meanings indicated in claimare inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.

Quinolin-2-one derivatives

Compounds of the formula I in which X, X, X, X, R, R, R, Q and Y have the meanings indicated in Claimare inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.

Compounds of the formula I in which Rand Rhave the meanings indicated in Claim, are inhibitors of ATR, and can be employed for the treatment of diseases such as cancer.

Tricyclic heterocylic derivatives

3-substituted cyclopentylamine derivatives

The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.

Hydroxystatin derivatives for the treatment of arthrosis

The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.

Acylguanidines for treating osteoarthritis

The present invention relates to compounds of the formula (I) and in particular medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.

Aminostatin derivatives for the treatment of arthrosis

Compounds of the formula I in which R, X, X, X, X, R, Rand q have the meanings indicated in Claimare inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

Piperazine derivatives as FASN inhibitors

Compounds of the formula I in which R, W, R, R, X, X, X, Xand q have the meanings indicated in claimare inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

3-aminocyclopentane carboxamide derivatives

Compounds of the formula I in which R, Y, R, X, X, Xand q have the meanings indicated in claim, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

1,3-Disubstituted cyclopentane derivatives

Compounds of the formula I in which R, R, R, R, X, X, X, X, q and W have the meanings indicated in claimare inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.

1,3-diaminocyclopentane carboxamide derivatives

Growing community of inventors

Weinheim, Germany

Christos Tsaklakidis