Massachusetts Institute of Technology

Christopher Rowlands

Edward Stuart Boyden

Moshe Ben Ezra

Young Gyu Yoon

Peter T C So

Elly Nedivi

Dushan N Wadduwage

Yi Xue

Kalen Berry

Jong Kang Park

Systems and methods herein provide improved, high-throughput multiphoton imaging of thick samples with reduced emission scattering. The systems and methods use structured illumination to modify the excitation light. A reconstruction process can be applied to the resulting images to recover image information free of scattering. The disclosed systems and methods provide high throughput, high signal-to-noise ratio, and high resolution images that are depth selective.

Systems and methods to reduce scattering in temporal focusing multiphoton microscopy

The information budget of a light field microscope is increased by increasing the field of view and image circle diameter of the microscope, while keeping the ratio of overall magnification of the microscope to the numerical aperture of the microscope unchanged. Alternatively, the information budget is increased by increasing the field of view and image circle diameter of the microscope by a first factor, while increasing the ratio of overall magnification of the microscope to the numerical aperture of the microscope by a smaller, second factor. In some cases, an infinity-corrected light field microscope has an overall magnification that is greater than the nominal magnification of the objective lens.

Methods and apparatus for stretched light field microscope

Growing community of inventors

London, United Kingdom

Christopher Rowlands