Factor Bioscience Inc.

Master Lock Company LLC

Brady Worldwide Corp.

Hellermanntyton Corporation

Massachusetts Institute of Technology

Aptiv Technologies Limited

Christopher Rohde

Matthew Angel

John Blomstrom

Glenn P Meekma

Gerard G Geiger

John N Heppner

Michael Toll

Franklin Kostas

Jonathan A Zick

Walter Patrick Trautfield

Jesse Alan Marcelle

Scott B Stevens

Thomas J Edwards

Gregg Allen Flender

Mark J Van Handel

Roy Alden Thompson

Robert A Rice

John Weber

Kenneth N Grandy, Sr

Mark D Johnson

Kevin Oliver

Noelle M Dye

Maryann Finiw

Olivier Ginet

Glen P Meekma

Paul Grade

Ricki Tarter

Katherine T Milbeck

Jonathan Mantes

Scott Kalous

Brent A Bandholz

Gary R Burmesch

Richard L Carriere

Justin Gallion

Alan J Suva

Reese L Vaughn

Mehmet Fatih Yanik

Kenneth W Phillips

Vince Leslie

Cody L Gilleland

Thaddeus C Stankowski

Charles Lasky

Steven J Lockwood

Michael Brojanic

Suzanne Schneider

Mark Johnson

Robert Rice

The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.

Methods and products for transfecting cells

The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.

Cationic lipids and transfection methods

The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.

Methods and products for transfection

The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules, including cells present in vivo. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.

Methods and products for nucleic acid production and delivery

The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.

Methods and products for expressing proteins in cells

The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.

Nucleic acid products and methods of administration thereof

A mounting bracket assembly for securement of elongate items, such as wires, cables, or other bundles items to a support structure. The mounting bracket assembly may include a clamp member defining a first clamp member and a second clamp member joined to the first clamp member by a hinge mechanism. The mounting bracket assembly may also include a locking mechanism, a wedge-shaped pawl having a plurality of teeth disposed within the slotted opening, and a mounting member defining a mounting aperture configured to receive an attachment feature therethrough.

Adjustable P-clamp with multiple mounting options

Growing community of inventors

Cambridge, MA, United States of America

Christopher Rohde