Mcw Research Foundation, Inc.

Christopher Quarles

Kathleen M Schmainda

B Douglas Ward

One or two sets of time course NMR data are acquired using an EPI pulse sequence in which either or both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. T* relaxation rates for GE and Trelaxation rates for SE are calculated from the acquired NMR signals and are corrected for extravasation of contrast agent into surrounding tissues. The gradient-echo signals and spin-echo NMR signals are employed along with the T* and Trelaxation rates to calculate hemodynamic parameter maps which are used as a measure of tumor angiogenesis.

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Milwaukee, WI, United States of America

Christopher Quarles