Aclaris Therapeutics, Inc.

Allergan, Inc.

Galderma Laboratories Inc.

Epi Health, LLC

Christopher Powala

Stuart D Shanler

Marc Barry Brown

Michael A Botta

Charles Rodney Greenaway Evans

Christopher Phillips

Thomas Nagler

Brian Beger

Sian Tiong Lim

Jack A DeJovin

Isabelle Jean DeJovin

Luis Rios

The present invention is directed to: a) a method of treating telangiectasia; b) a method of treating inflammatory lesions; and c) a method of treating two or more symptoms ofselected from erythema, telangiectasia, or inflammatory lesions comprising topical administration of a pharmaceutical composition comprising oxymetazoline and a pharmaceutically acceptable excipient.

Pharmaceutical cream compositions of oxymetazoline and methods of use

Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts,accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.

Peroxide formulations and methods and applicators for using the same

Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts, condyloma accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.

The present invention provides pharmaceutical cream compositions comprising oxymetazoline and methods for treating rosacea and other skin disorders as described herein using the above cream compositions.

Pharmaceutical cream compositions and methods of use

Methods, compounds, and topical formulations for treatment of telangiectasias are disclosed. The methods comprise topically applying a composition comprising an &#x3b1;-adrenergic receptor agonist to telangiectatic skin. Amelioration of telangiectasia symptoms begins within minutes after topical application of a disclosed composition. A single application can significantly lessen telangiectasia discoloration for at least about 2 hours.

Compounds, formulations, and methods for ameliorating telangiectasias

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Radnor, PA, United States of America

Christopher Powala