Manus Bio Inc.

Givaudan S.a.

Manus Biosynthesis, Inc.

Christopher Pirie

Ajikumar Parayil Kumaran

Souvik Ghosh

Liwei Li

Chin Giaw Lim

Anthony Qualley

Jason Eric Donald

Ryan Philippe

Christine Nicole S Santos

Aaron Love

Hsien-Chung Tseng

Geoff Marshall-Hill

Chin-Giaw Lim

Hong Nan

Martin Preininger

Huey-Ming Mak

Srishti Tibrewala

In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.

Metabolic engineering for microbial production of terpenoid products

The present invention relates to methods for producing oxygenated terpenoids. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.

Methods for production of oxygenated terpenes

The present disclosure relates to methods for producing oxygenated terpenoids, and preparation of compositions and formulations thereof. Polynucleotides, derivative enzymes, and host cells for use in such methods are also provided.

The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in() host cells that functionally express engineered P450 enzymes.

Increasing productivity ofhost cells that functionally express P450 enzymes

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Cambridge, MA, United States of America

Christopher Pirie