Aclaris Therapeutics, Inc.

Biogen Idec Ma Inc.

Biogen Ma Inc.

Elan Pharmaceuticals, Inc.

Dermbiont, Inc.

Servier IP UK Limited

Christopher Phillips

Marc Barry Brown

Michael A Botta

Charles Rodney Greenaway Evans

Stuart D Shanler

Christopher Powala

Thomas Nagler

Brian Beger

Sian Tiong Lim

David J Burke

James Callaway

Barbara Horsey O'Connor

Sherwood Russ Lehrman

Shaun E Buckley

Emma Taylor

Nadejda Soukhareva

Mark De Souza

Brendan Philip Brady

Gianfranco Fornasini

Vanessa Alexandra Cofré Urrutia

Ravi Kumar Pandrapragada

Karl Beutner

Barbara Horsey O'connor

Aspects of the invention include polyalkylene oxide-asparaginase compositions. In some instances, the composition is a lyophilized storage stable composition. In some instances, the lyophilized compositions include one or more of a buffer, a salt, and a sugar. Aspects of the invention further include methods of making the compositions. The compositions find use in a variety of applications, e.g., in the treatment of a neoplastic condition in a subject.

Formulations of polyalkylene oxide-asparaginase and methods of making and using the same

Provided herein are compositions comprising ruboxistaurin free base and its salts thereof and methods of use for treating conditions of the skin.

Compositions and formulations for use of a PK inhibitor for the prevention, treatment, and improvement of skin diseases, conditions, and disorders

A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.

Immunoglobulin formulation and method of preparation thereof

Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts,accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.

Peroxide formulations and methods and applicators for using the same

Embodiments are directed to a stable composition comprising stabilized hydrogen peroxide and 2-propanol and applicators configured to store, dispense, and apply such stable compositions. Such compositions may be used to treat skin conditions such as warts, condyloma accuminatum, molluscum contagiosum, acrochordons, seborrheic keratosis, or a combination thereof. Some embodiments also describe take home compositions, in office compositions, over-the-counter compositions, and kits for the use of such compositions.

Method for treating multiple sclerosis and crohn's disease

Growing community of inventors

Doylestown, PA, United States of America

Christopher Phillips