Carefusion 2200, Inc.

Christopher Matthew McGinley

Kenneth Bruce Thurmond, Ii

Satish Degala

Brandon Borowski

Brandon Dellaringa

John A Krueger

Dan Zimbler

Taryn Bagby

Maleeha Mashiatulla

A system for applying a lavage fluid to a surface, the system having a body configured to house a lavage fluid, an application member in fluid communication with the body, the application member being configured to dispense the lavage fluid, and a warming component configured to communicate with the body so as to transfer energy from the warming component to the body sufficient to warm the lavage fluid housed in the body.

Lavage systems and devices having warming component

An antiseptic solution comprising a pH-dependent antimicrobial agent, the pH-dependent antimicrobial agent having an operative pH range, wherein the solution has a pH on storage that is lower than the operative pH range. Applicators for applying the antiseptic solution and methods of using the antiseptic solution and applicators are also provided.

Method for decontaminating a surface with a pH-adjusted antiseptic solution and applicator

A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85&#xb0; C. to about 135&#xb0; C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.

Systems, methods, and devices for sterilizing antiseptic solutions

Antiseptic solutions and applicators

A method for sterilizing an aqueous antiseptic solution, the method comprising providing a container containing the aqueous antiseptic solution, the aqueous antiseptic solution comprising a bis-(dihydropyridinyl)-decane derivative or a biguanide, heating the aqueous antiseptic solution to a predetermined temperature, maintaining the aqueous antiseptic solution at the predetermined temperature for a predetermined time, and terminating the heating of the aqueous antiseptic solution when the predetermined time expires. The predetermined temperature and the predetermined time are selected such that after terminating the heating, the aqueous antiseptic solution is sterile.

A method for sterilizing an antiseptic solution includes providing a plurality of containers containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85&#xb0; C. to about 135&#xb0; C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution in the plurality of containers to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution in the plurality of containers has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and have a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.

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Highland Park, IL, United States of America

Christopher Matthew McGinley