Alza Corporation

Christopher M Ohms

Jeffrey Wayne Etter

Patrick S-l Wong

Vincent Joseph Ferrari

James Horvath

Nathan Roth

Andrew I Poutiatine

Miriam A Martin

Joyce C Anthony

Radomir N Vukadin

The present invention is directed to an oral active agent delivery system comprising improved flow controllers. A hollow tubular member (10) containing the active agent formulation and having a fluid passing controller (14) is placed at one end (16) into a fluid and at a second end (18) into a patient's mouth. The active agent is delivered when the patient sips on the end of the chamber. The improved controllers prevent leakage of the active agent formulation.

Flow controller configurations for an active agent delivery device

The present invention is directed to a closure system for an oral active agent delivery device. The device comprises an elongate tubular member having first and second ends. The closure system includes a deformable closure means adapted to allow delivery of the active agent upon deformation. The closure system prevents spillage and maintains the integrity of the dose within the device. In use, the closure system is deformed and separated from the second end of the tubular member, liquid is drawn up into the first end of the member, and the liquid and active agent are drawn out of the second end of the member and into the patient's mouth.

Closure system for an active agent delivery device

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San Mateo, CA, United States of America

Christopher M Ohms