Diamond Innovations. Inc.

University of Central Florida Research Foundation Inc

Christopher Long

Andrew Gledhill

James J Hickman

Alexanne Johnson

Kai Zhang

Kazi Tasneem

Thomas R Anthony

Mark Philip D'Evelyn

Dong-Sil Park

Clifford L Spiro

Joel Michael Vaughn

Valeriy Konovalov

Joseph M Rhodes

Maria Stancescu

Susanne Sowers

Peter Molnar

Yue Meng

Christopher McAleer

Shuang Ji

Alexander Smith

Kristen Pirozzi

Christopher Mcaleer

Disclosed herein are microfluidic systems with recirculation of fluid and computer-implemented methods of calculating conditions within the microfluidic systems. The microfluidic systems include a computing device and a microfluidic device having first and second reservoirs, at least one chamber, and a fluid path connecting the first reservoir, the chamber, and the second reservoir. The methods for calculating conditions include receiving a first reservoir fluid volume, a second reservoir fluid volume, a first concentration, and a second concentration. The methods further include receiving a time-dependent imposed pressure difference between the first reservoir and the second reservoir, then determining a hydraulic pressure difference and an effective pressure difference. The effective pressure difference is used to account for reactions occurring within the microfluidic device and to determine the value of the condition within the microfluidic device. Methods of performing an experiment using a microfluidic device with recirculation are also disclosed herein.

Model for fluid and mass transport in a recirculating microfluidic system

In an aspect, disclosed herein are physiological devices and systems, and components thereof, used to evaluate cardiac parameters and arrhythmogenic mechanisms. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Devices, systems, and methods for evaluating cardiac parameters

Disclosed herein are devices comprising one or more cantilevers comprising one or more neuromuscular junctions formed by a co-culture of myotubes and motoneurons. Disclosed herein are methods of using the disclosed devices comprising one or more cantilevers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Devices and methods comprising neuromuscular junctions

Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body () includes an annular region () of inter-bonded diamond grains having a first characteristic property and a core region () of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Polycrystalline diamond bodies having annular regions with differing characteristics

A superabrasive cutter and a method of making the superabrasive cutter are disclosed. The superabrasive cutter may comprise a plurality of polycrystalline superabrasive particles and about 0.01% to about 4% by weight of the superabrasive particles of a dopant as evaluated prior to a high pressure/high temperature process. The dopant may be immiscible with a catalyst for forming the polycrystalline superabrasive particles.

PDC cutter with chemical addition for enhanced abrasion resistance

Polycrystalline diamond bodies having an annular region of diamond grains and a core region of diamond grains and methods of making the same are disclosed. In one embodiment, a polycrystalline diamond body includes an annular region of inter-bonded diamond grains having a first characteristic property and a core region of inter-bonded diamond grains bonded to the annular region and having a second characteristic property that differs from the first characteristic property. The annular region decreases in thickness from a perimeter surface of the polycrystalline diamond body towards a centerline axis.

Polycrystalline diamond cutting elements having enhanced thermal stability, drill bits incorporating the same, and methods of making the same are disclosed herein. In one embodiment, a cutting element includes a substrate having a metal carbide and a polycrystalline diamond body bonded to the substrate. The polycrystalline diamond body includes a plurality of diamond grains bonded to adjacent diamond grains by diamond-to-diamond bonds and a plurality of interstitial regions positioned between adjacent diamond grains. At least a portion of the plurality of interstitial regions comprise a non-catalyst material, a catalyst material, metal carbide, or combinations thereof. At least a portion of the plurality of interstitial regions comprise non-catalyst material that coats portions of the adjacent diamond grains such that the non-catalyst material reduces contact between the diamond and the catalyst.

Polycrystalline diamond cutting elements having non-catalyst material additions

Polycrystalline diamond cutting elements having enhanced thermal stability, drill bits incorporating the same, and methods of making the same are disclosed herein. In one embodiment, a cutting element includes a substrate having a metal carbide and a polycrystalline diamond body bonded to the substrate. The polycrystalline diamond body includes a plurality of diamond grains bonded to adjacent diamond grains by diamond-to-diamond bonds and a plurality of interstitial regions positioned between adjacent diamond grains. At least a portion of the plurality of interstitial regions comprise lead or lead alloy, a catalyst material, metal carbide, or combinations thereof. At least a portion of the plurality of interstitial regions comprise lead or lead alloy that coat portions of the adjacent diamond grains such that the lead or lead alloy reduces contact between the diamond and the catalyst.

Polycrystalline diamond cutting elements having lead or lead alloy additions

Methods of making polycrystalline diamond bodies having annular regions with differing characteristics

A superabrasive material and method of making the superabrasive material are provided. The superabrasive material may comprise a superabrasive crystal having an irregular surface. The superabrasive material further comprises a plurality of structure defects within the superabrasive crystal. The plurality of structure defects may cause micro-chipping when used as grinding materials.

Single crystal CBN featuring micro-fracturing during grinding

A superabrasive cutter and a method of making the superabrasive cutter are disclosed. The superabrasive cutter may comprise a plurality of polycrystalline superabrasive particles and about 0.01% to about 4% by weight of the superabrasive particles of a metal or metal alloy. The metal or the metal alloy may be immiscible with a catalyst for forming the polycrystalline superabrasive particles.

A system and a method of testing a superabrasive cutter are disclosed. The system of testing a superabrasive cutter may comprise a spinning wheel holding the superabrasive cutter; a rock feeding into a rotation of the superabrasive cutter on the spinning wheel; and a plurality of sensors operably attaching to the spinning wheel and the rock to detect properties of the superabrasive cutter. The method of testing a superabrasive cutter may comprise steps of attaching a superabrasive cutter to a spinning wheel; moving a rock into a rotation of the superabrasive cutter on the spinning wheel; and communicably coupling a first sensor to the superabrasive cutter.

Laboratory assessment of PDC cutter design under mixed-mode conditions

A superabrasive material and method of making the superabrasive material are provided. The superabrasive material may comprise a superabrasive crystal and a plurality of particles. The plurality of particles may be included within the superabrasive crystal. The plurality of particles may comprise a non-catalyst material.

Growing community of inventors

Westerville, OH, United States of America

Christopher Long