University System of Maryland

Christopher Kitchen

William E Bentley

Gregory F Payne

Reza Ghodssi

Deanna L Kelly

Thomas E Winkler

Eunkyoung Kim

George Banis

Mijeong Kang

Methods are provided that allow global access to redox-based molecular information by coupling electrochemical measurements with signal processing approaches. More specifically, the disclosure provides methods that rely on the use of redox probes to assay samples for redox activities that act to exchange electrons with the probe thereby generating detectable optical and electrochemical signature signals that can then be assigned to a sample feature of interest. In particular embodiments, the disclosed assay methods are useful for diagnosis and prognosis of disorders, such as schizophrenia, that are found to be associated with a specific redox-based signature within a subject sample.

Redox probing for chemical information

Growing community of inventors

Ellicott City, MD, United States of America

Christopher Kitchen