Iowa State University Research Foundation Inc

United States of America, As Represented by the Secretary of Agriculture

Pig Inprovement Company UK Limited

Biotechnology Research and Development Corporation

Pig Improvement Company Uk, Limited

Christopher K Tuggle

Max F Rothschild

Graham Stuart Plastow

Amy L Vincent

Alan J Mileham

Thomas J Stabel

Martha A Mellencamp

Olwen Irene Southwood

Carol D Jacobson

Jason Wayne Ross

Albert E Freeman

Christy Gladney

Amber Stumbaugh

Martine Schroyen

David A Vaske

Tun-Ping Yu

Lori A Messer

Carole Sargent

Emily H Waide

Xianwei Shi

Jack C M Dekkers

N Matthew Ellinwood

Lena Marklund

The genetic basis for severe combined immunodeficiency disease (SCID) in pigs is described. In addition, tests for detecting pigs that are carriers for SCID or pigs with SCID are also described. Further, methods for producing pigs or herds of pigs with SCID are also described. Further, methods and compositions for treating, ameilioraing, inhibiting or correcting SCID are provided.

Genetic test and genetic basis for SCID in pigs

Disclosed herein are genetic markers for animal litter size, methods for identifying such markers, and methods of screening animals to determine those more likely to produce larger litters and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the prolactin receptor gene.

Prolactin receptor gene as a genetic marker for increased litter size in animals

A method for determining improved disease resistance in animals is disclosed. The method assays for a novel genetic alleles of the BPI gene of the animal. The alleles are correlated with superior disease resistance. Novel nucleotide sequences, assays and primers are disclosed for the methods of the invention.

Genetic markers for improved disease resistance in animals (BPI)

A method for determining improved innate immunity, disease resistance or performance in animals is disclosed. The method involves assays for a genetic differences in the NRAMP1 gene of the animal which is associated with superior disease resistance. Novel NRAMP1 sequence, assays, and compositions for identifying the presence of absence of these alleles are provided.

Genetic markers for screening animals for improved disease resistance (NRAMP)

Disclosed herein are genetic markers for favorable reproductive traits in animals such as litter size, and weaning weight. Methods for identifying such markers, and methods of screening animals to determine those more likely to produce favorable reproductive traits and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the pig reproductive genes, including retinol binding protein 4, retinoic acid receptor gamma, melatonin receptor 1a, and vascular cell adhesion molecule 1

Genes and genetic markers for improved reproductive traits in animals

Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters and preferably selecting those pigs for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the pig prolactin receptor gene.

Prolactin receptor gene as a genetic marker for increased litter size in

Genetic markers in the bovine PIT-1 gene are disclosed which are associated with increased milk production and increased protein and fat content in cattle. Further, novel sequence data from intron regions of the gene are disclosed which may be used in a PCR test to screen for the presence of the marker.

Genetic marker for improved milk production traits in cattle

Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters and preferably selecting those pigs for future breeding purposes based on the ESR polymorphisms. The markers are based upon the presence or absence of certain polymorphisms in the pig estrogen receptor gene. Preferably, the polymorphism is a restriction fragment length polymorphism (RFLP).

Genetic markers for pig litter size

Growing community of inventors

Ames, IA, United States of America

Christopher K Tuggle