Platypus Technologies, LLC

Wisconsin Alumni Research Foundation

Other

University of California

Imbed Biosciences, Inc.

Wound Engineering LLC

Trophic Solutions LLC

Christopher John Murphy

Nicholas Lawrence Abbott

Barbara Israel

Jonathan McAnulty

Ted W Reid

Doug Hansmann

Nathan Lockwood

Sean Paul Palecek

Jeffrey C Mohr

Jugal Gupta

Elise Huang

Vijay Krishna Raghunathan

Mark J Mannis

I-Hsin Lin

Rishabh Jain

Yan-Yeung Luk

Bharat Raj Acharya

Juan J Depablo

Chang-Hyun Jang

Li-Lin Cheng

Sara M Thomasy

Sean Francis Campbell

Joshua T Morgan

Joshua Wood

Syrus Soltaninassab

Paul Russell

Michael E Selsted

Robert I Lehrer

Juan Jose De Pablo

Tomas Ganz

James S Cullor

Ankit Agarwal

Karla Anhalt

Gordon S Mitchell

Erik R Wisner

Nicholas Abbot

Josh Sotos

Francis J Golder

Bradley A Foster

Renee Herber

John H Doval

Joseph Burkholder

Kaitlin Murphy

Bernardo Yañez-Soto

Keren Hulkower

Michael Bonds

Karla Hollister

The present invention relates to methods and compositions for modifying mucous membranes. In particular, the present invention relates to treating diseases associated with mucous membranes by changing the intrinsic chemical composition and/or physical features of a target mucous membrane.

Methods and compositions for modifying mucous membranes

The present invention relates to methods and devices for characterizing wounds, and in particular to the use of Raman spectroscopy to characterize the state of healing of a wound.

Method of characterizing wounds with raman spectroscopy

Provided are methods for assessment of surface rugosity of a layer of live cells using tools that determine contact angle and contact angle hysteresis.

Methods of diagnosing diseases of mucosal surfaces

The present invention relates to methods and compositions for wound healing. In particular, the present invention relates to promoting and enhancing wound healing by utilizing cross-linker covalent modification molecules to attach and deliver wound active agents to a wound. In addition, the present invention provides methods and compositions utilizing oppositely charged polymers to form a polyelectrolyte layer on a wound surface. The invention further relates to incorporating wound active agents into a polyelectrolyte layer for delivery to a wound.

Methods and compositions for wound healing

Method of characterizing wounds with Raman spectroscopy

The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other biophotonically based assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal or other biophotonically based assay formats.

Devices for cell assays

The present invention relates to method, system, and composition for modulating the compliance of the trabecular meshwork, which may provide treatment to glaucoma.

Methods of modulating compliance of the trabecular meshwork

The present invention relates to the field of detection of viruses, and in particular to detection of viruses using a liquid crystal assay format. In the present invention, virus binding in a detection region is identified by changes in liquid crystal orientation caused by virus binding independent orientation caused by any topography associated with the detection region.

Liquid crystal based analyte detection

The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.

Substrates, devices, and methods for quantitative liquid crystal assays

The present invention relates to a deformable object to be implanted into a surgical site (exemplified by but not limited to a cornea lenticule, e.g., that could be native corneal tissue or a synthetic or biosynthetic construct), surgical instrumentation for altering the curvature and arc length of the deformable object to be implanted (e.g. corneal lenticule), as well as methods for introduction of the deformable object into the specifically prepared wound bed and for introduction of the deformable object.

Implanting oversized objects into surgical beds

Devices and methods for using changes in the defects in micrometer sized dispersed liquid crystal domains to detect or quantify analytes in a test sample, including endotoxin lipopolysaccharide (LPS), are disclosed. The dispersed liquid crystal microdomains are exposed to the test sample, and any changes in the number of defects in the liquid crystal microdomains are detected by detecting changes in the anchoring configuration of the microdomains. Such changes in anchoring configuration indicate the presence of analyte in the test sample.

Analyte detection using liquid crystals

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Madison, WI, United States of America

Christopher John Murphy