Mayo Foundation for Medical Education and Research

Lean Medical Technologies, Inc.

The University of Texas System

Apollo Endosurgery, Inc.

Christopher John Gostout

Richard Merrell Chesbrough

Naresh Thomas Gunaratnam

Vishal J Bhagat

William Gerald O'Neill

Vladimir Mitelberg

Donald K Jones

Pankaj Jay Pasricha

Brett E Naglreiter

Jose G De La Mora Levy

J Landon Gilkey

David Y Yuan

A gastrointestinal device and method for retrieving the device are disclosed. The device may include a stent including a plurality of strands forming first and second ends, the strands configured to move between a retrieval configuration, with substantially parallel strands, and a deployed configuration, wherein the strands form proximal and distal portions having first and second diameters larger than the pyloric sphincter. The device may include a connector assembly including proximal, middle, and distal connectors. The middle connector may be coupled to the proximal and distal connectors when the strands are in the deployed configuration. The strands may be attached to the proximal and distal connectors and the first and second ends. The device may include a release mechanism configured to decouple the proximal connector from the middle connector. Decoupling of the proximal and middle connectors may allow the strands to move from the deployed to retrieval configuration.

Gastrointestinal device

A gastrointestinal device for reducing flow through a pyloric sphincter of a patient is disclosed. The device may include a stent including a plurality of strands forming first and second ends, the plurality of strands configured to form a proximal portion having a proximal diameter and a distal portion having a distal diameter. The proximal and distal diameters may be larger than a diameter of the pyloric sphincter and the proximal diameter may be larger than the distal diameter. The device may include a connector assembly including proximal and distal connectors, the plurality of strands being attached to the proximal and distal connectors at the first and second ends. The connector assembly may further include a middle portion extending between the proximal and distal connectors. The middle connector may extend within the plurality of strands, and may be unattached to the plurality of strands.

Apparatus and methods for internal surgical procedures are disclosed. The apparatus and methods may involve supporting internal body locations, creating submucosal separations (blebs), and/or for resecting mucosal tissue separated from underlying tissue by a bleb.

Apparatus and methods for internal surgical procedures

A gastrointestinal device and method for inserting the device are disclosed. The device may include a stent including a plurality of strands. The stent may move between an insertion configuration, wherein the plurality of strands are substantially parallel, and a deployed configuration, wherein the plurality of strands form a proximal portion having a first diameter and a distal portion having a second diameter. The first and second diameters may be larger than a diameter of the pyloric sphincter. The device may include a connector assembly including proximal and distal connectors attached to the strands. A cable including an engagement portion may be configured to releasably couple to the distal connector and to cause the strands to move from the insertion configuration to the deployed configuration when the engagement portion is coupled to the distal connector and force is applied to the cable in a direction toward the proximal connector.

Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided.

Methods and systems for performing submucosal medical procedures

Kits and methods for submucosal endoscopic access into body cavities such as the peritoneal cavity and the posterior mediastinum through a submucosal endoscopic procedure in which an opening is formed through the muscularis propria within a bleb. The procedure may result in a mucosal flap formed by separated mucosal tissue within the bleb and the mucosal flap may be advantageously used to assist in closure of the opening.

Growing community of inventors

Rochester, MN, United States of America

Christopher John Gostout