Glaxo Group Limited

Glaxosmithkline Intellectual Property Development Limited

Smithkline Beecham Corporation

Glaxogrouplimited

Glaxco Group Limited

Christopher James Lunniss

Alison Judith Redgrave

Julie Nicole Hamblin

Brian Edgar Looker

Joelle Le

Nigel James Parr

Paul Spencer Jones

Suzanne Elaine Keeling

Charlotte Jane Mitchell

Ian Robert Baldwin

Timothy John Ritchie

Kenneth David Down

Simon Gaines

Christian Alan Paul Smethurst

Paul Faulder

Juliet Kay Simpson

John Edward Robinson

Istvan Kaldor

Colin David Eldred

Stephen Barry Guntrip

Michael David Barker

Brian Evans

Katherine Louise Jones

Michael David Woodrow

Stuart Holman

Anthony William Dean

Yoshiaki Washio

Derek Peter Reynolds

Zoe Alicia Harrison

Sharon Lisa Gough

Mika Kristian Lindvall

Tracy Jane Redfern

The invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity. 

Compounds

The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity. 

Benzpyrazol derivatives as inhibitors of PI3 kinases

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity. 

4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases

There are provided according to the invention novel compounds of formula (I)  or pharmaceutically acceptable salts thereof, wherein R, RRRand Rare as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.

Quinoline derivatives as phosphodiesterase inhibitors

Compounds of formula (I): and uses of such compounds are described.

Compounds for use as surfactants

Compounds of formula (I): or salts or solvate thereof, wherein:

A method for treating respiratory disorders comprises administering to a patient a pharmaceutical aerosol formulation comprising: (i) a compound of formula (I) 

Alkanoic acid derivatives

Compounds of formula (I) or a salt or solvate thereof, wherein:

Carboxylic acid compounds for use as surfactants

A pharmaceutical aerosol formulation that includes a particulate medicament, one or more fluorocarbon or hydrogen-containing fluorocarbon propellants and a compound of the general formula (I) or a salt or solvate thereof is disclosed, wherein wherein at least one substituent of formula B contains at least one fluorine atom and each Cfluoroalkyl- moiety contains one or more fluorine atoms but not more than 3 consecutive perfluorinated carbon atoms. Compounds of formula (I) and uses of such compounds are also disclosed.

Surfactant compounds and uses thereof

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Stevenage, United Kingdom

Christopher James Lunniss