University of Pennsylvania

Christopher J Wilson

Virgil Percec

Daniela A Wilson

Andrew Edward Feiring

Brad Matthew Rosen

Pawaret Leowanawat

Andrew D Hughes

The invention concerns compounds of the formula: X&#x2014;(Y)wherein: X is Formula (X), each Y is the same or different and is Formula (Y) &#x2014;O&#x2014;[CH&#x2014;CH(OH)&#x2014;CH&#x2014;O&#x2014;]&#x2014;H; or &#x2014;C(OR); R, R, R, R, R, R, R, Rare each, independently, &#x2014;(CHCHO)&#x2014;R, &#x2014;[CHCH(OH)CHO]H, OR, &#x2014;O(CH)R, or &#x2014;(CH)R; each Ris independently ORor OH; R, Rand Rare each, independently, H or C-Calkyl; Ris &#x2014;NHClor &#x2014;NHBoc; t is an integer from 2 to 6; m, n, and p are each, independently, an integer from 1 to 12; and each q, r, and s is 0 or 1 and the sum of q+r+s is at least 2. 

Amphiphilic Janus-dendrimers

The present invention concerns the design of an environmentally friendly and efficient fluorous phase based on dendritic architectures containing short semifluorinated groups on their periphery.

Fluorous dendrimers and methods for production thereof

The invention concerns processes for the synthesis of a compound of the formula: wherein: Rand Rare each, independently, C-Calkyl, COR, OR, R(OR), or C-Caryl; R-Rare each, independently, C-Calkyl or C-Caryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:&#x2014;contacting a compound of the formula H0-R-0H with BHand a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where Ris a C-Chydrocarbon group and X is a halogen, OMs or OTs;&#x2014;contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen. 

Growing community of inventors

Rotherham, United Kingdom

Christopher J Wilson