Flipsi Ltd.

Michigan Critical Care Consultants, Inc.

Christopher J Plott

Jeffrey Stephen Plott

Robert L Beane, Iii

Raymond DiTullio

The disclosure relates to devices and methods for extracorporeal conditioning of blood. Extracorporeal blood oxygenators and blood oxygenator components, such as conditioning modules, are described. An extracorporeal blood oxygenator includes a conditioning module having an external frame, an inlet cover, an outlet cover, and an internal chamber. A fiber assembly is disposed within the internal chamber and a potting material on the fiber assembly creates a circumferential seal that defines a passageway through the fiber assembly having a substantially circular cross-sectional shape. A fluid inlet is in fluid communication with the passageway, has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly, and has an internal curvilinear surface adjacent the fiber assembly. A fluid outlet on the opposite side of the fiber assembly also has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly.

Devices and methods for extracorporeal conditioning of blood

Membrane oxygenators useful in a variety of medical situations, including various short-term procedures and relatively longer-term life support, and components of membrane-based oxygenators, such as conditioning modules for exchanging oxygen for carbon dioxide during extracorporeal conditioning of blood, are described. A conditioning module includes a plurality of mats of hollow fibers and a potting material disposed throughout the peripheral edges of the mats to create a circumferential seal that defines a passageway through the plurality of fiber mats having a substantially circular cross-sectional shape. The circumferential seal defines an effective fiber length for each of the hollow fibers. A resisting member is disposed across the proximal ends of at least some of the hollow fibers and is adapted to resist fluid flow into each of the hollow fibers based on the effective fiber length of the particular hollow fiber.

Membrane oxygenator with gas exchange fiber lumen access based on fiber effective length

Beverage container insert

Beverage container

A receptacle has at least one elastomeric sidewall with a contoured non-linear shape defining a container with a predetermined volume for housing a substance to be contained. The at least one sidewall includes a substance-contacting surface. The receptacle is fully reversibly eversible to transform between a first stable conformation with the substance-contacting surface facing inward and a second stable conformation with the substance-contacting surface facing outward allowing for facile cleaning and drying of the substance-contacting surface. The at least one elastomeric sidewall possesses sufficient structural strength to stand upright in the first and second stable conformations without extraneous support. The receptacle can include a cap and an attachment joint for securing the cap to the elastomeric receptacle.

Growing community of inventors

Dexter, MI, United States of America

Christopher J Plott