Rainin Instrument Co., Inc.

Bio-rad Laboratories, Inc.

Medtronic, Inc.

Rainin Instrument, LLC

Neovista Inc.

Rainin Intstrumental Co., Inc.

Christopher F Kelly

Kenneth Rainin

James S Petrek

Kevin D Ness

Donald Masquelier

William D Homberg

Steven T Nielsen

Haakon T Magnussen

David J Lemieux

Mark T Stewart

Paul T Rothstein

David E Francischelli

William W Malecki

Benjamin K Yaffe

Douglas H Gubbin

Thomas Daigle

David J Kim

Christopher Plott

Brett S Bowman

Adam Podbelski

Mark A Thompson

Darrin E Dickerson

Paul K Chadwick

Jay Daulton

Kristopher M Konawalik

Kent Gordon Moriarty

Mark A Diel

Benjamin Woodward

Bill Vermeere

William Metzger

David Beaulieu

Guang Gun (Max) Chen

Haakon T Magnujssen, Jr

Donald A Masquelier

A system, including method and apparatus, for generating droplets suitable for droplet-based assays. The disclosed systems may include either one-piece or multi-piece droplet generation components configured to form sample-containing droplets by merging aqueous, sample-containing fluid with a background emulsion fluid such as oil, to form an emulsion of sample-containing droplets suspended in the background fluid. In some cases, the disclosed systems may include channels or other suitable mechanisms configured to transport the sample-containing droplets to an outlet region, so that subsequent assay steps may be performed.

Method of emulsion formation and modification

A method of surgical dissection of tissue with a dissector comprising: an elongate shaft comprising a proximal portion and a distal portion, wherein the distal portion comprises a plurality of segments that articulate with respect to one another and the plurality of segments includes a distal segment having a distal end; and a handle attached to the proximal portion of the shaft, wherein the handle comprises controls for articulating the plurality of segments of the distal portion of the shaft with respect to one another, comprising the steps of: positioning the distal end of the dissector in a body; advancing the distal end through the body to dissect tissue; and simultaneously articulating the plurality of segments with respect to one another. A method of surgical dissection of tissue and guiding a second device to a desired physiological location with a first device.

Method of surgical dissection and/or guidance of other medical devices into body

Device for generating droplets

Droplet generation for droplet-based assays

A handheld radiation delivery system is disclosed that includes a two-part delivery module comprising a reusable portion that contains a radioactive source wire and a disposable portion that includes a drive assembly for moving the radioactive source wire between storage and treatment positions. A disposable applicator tip is provided that includes a cannula for receiving the radioactive source wire when in the treatment position and a mechanism for limiting the number of uses of the device. A handheld cable actuator is operatively connected to the disposable portion of the handpiece to impart motion to the source wire.

Handheld radiation delivery system

An air displacement pipette having axially spaced annular sealing and substantially cylindrical lateral support zones on the outer surface of the pipette's mounting shaft for mating with axially spaced annular sealing and substantially cylindrical lateral support regions on the inner surface of a pipette tip, whereby the pipette tip is easily and firmly mountable on and easily ejectable from the pipette tip mounting shaft by the application of minimal axial mounting and ejection forces.

Pipette with improved pipette tip mounting shaft

A bilaterally symmetrical lightweight hand holdable battery powered microprocessor controlled electronic pipette including an axially elongated hollow housing having a vertically extending longitudinal axis. An upper portion of the housing includes a forward compartment containing a forwardly facing alpha-numeric display, a plurality of columns of forwardly facing control keys and plurality of forwardly facing trigger switches arranged in a vertically spaced pattern such that a user in gripping a lower handle portion of the housing in either his or her right or left hand can easily reach with his thumb the control keys, trigger switches as well as a push button of a pipette tip ejector.

Bilaterally symmetrical battery powered microprocessor controlled lightweight hand-holdable electronic pipette

Pipette tip

A battery powered, microprocessor controlled portable electronic pipette, comprising a hand holdable housing supporting a battery, a linear actuator for driving a plunger lengthwise in a cylinder to aspirate and dispense fluid into and from a pipette tip extending from the housing and a control circuit for the linear actuator. The linear actuator is powered by the battery and comprises a stepper motor with current receiving windings for electromagnetically driving a rotor to impart the lengthwise movement to the plunger. The control circuit includes (i) a user controllable microprocessor powered by the battery and programmed to generate drive signals for the stepper motor, (ii) a display supported by the housing and electrically connected to the microprocessor, (iii) user actuateable control keys supported by the housing and electrically connected to the microprocessor for generating within the microprocessor pipette mode of operation, liquid pick up volume, liquid dispense, pipette speed of operation and pipette reset signals for controlling operation of the pipette and alpha-numeric user readable displays on the display, (iv) a memory having tables of data stored therein and accessible and useable by the microprocessor to control operations of the pipette, and (v) user actuateable switches supported by the housing for triggering pipette operations selected by user actuation of the control keys.

Battery powered microprocessor controlled hand portable electronic pipette

A plastic pipette tip easily and firmly mountable on and easily ejectable from a pipette mounting shaft of a pipette by application of relatively small axial mounting and ejection forces of about six and three (3) pounds respectively. The pipette tip includes a tubular proximal portion comprising (i) a frusto-conical open upper end portion having an inner diameter at its upper end greater than the diameter of a mounting shaft of the pipette to which the pipette tip is to be mounted, (ii) a hollow mid-portion and (iii) an annular sealing region at a junction of the open end and mid-portions. The annular sealing region has an inner diameter less than &ldquo;x&rdquo; and is designed to engage a lower end of a sealing zone of the mounting shaft to stretch radially outward as the mounting shaft is guided and stably oriented in the proximal portion thereby creating a fluid tight seal between the sealing zone and the sealing region.

Easy eject pipette tip

Growing community of inventors

Larkspur, CA, United States of America

Christopher F Kelly