Johns Hopkins University

Christopher E Bradburne

Lucy M Carruth

Matthew Yeager

Jason E Tiffany

Leslie H Hamilton

David B Taubenheim

Emily P English

The presently disclosed subject matter provides a novel approach for the treatment, prevention, and diagnosis of Cap-Snatching virus infections, particularly all classes of human influenza, including pandemic influenza. The methods involve the use of constructs for RNA-interference (RNAi).

Influenza-activated constructs and methods of use thereof

A capacitive liquid crystal (LC) biosensor for sensing a target biological agent includes a support board; a flow channel on the support board, the flow channel having an inlet port at a first end and an exit port at a second end; at least two electrodes, the at least two electrodes including a first electrode on a flow channel first surface and a second electrode on a flow channel second surface opposite the flow channel first surface; an electricity source connected to the first electrode and the second electrode; and an LC sensor array positioned within the flow channel. An LC sensor array includes a sensor support surface; wells positioned on the sensor support surface; an organic LC phase within each of the plurality of wells; and an aqueous phase having an analyte positioned above the organic LC phase within the wells.

Capacitive liquid crystal biosensors

Growing community of inventors

Arlington, VA, United States of America

Christopher E Bradburne