Canon U.s.a., Inc.

Christopher Douglas Brushett

Emily Chernich

Disclosed are an apparatus and method for finding a range of lumen clearance, including positioning an imaging probe in a lumen such that the probe tip is positioned to irradiate a target area; acquiring a first set of images of an inside of the lumen while performing a non-flush pullback operation with the probe; analyzing the first set of images to determine a location of the probe tip with respect to a guide catheter; calculating a range of lumen clearance based on the location; and acquiring a second set of images of the inside of the lumen while performing a flush pullback operation only within the calculated range of lumen clearance. Calculating the range of lumen clearance includes calculating a pullback distance from the target area to the distal end of the guide catheter. The method further includes calculating a volume of contrast agent for clearing the calculated pullback distance.

Range finder for OCT luminal clearance

A multimodality system includes first and second modalities, an optical probe, a detector, and a sheath with a known fluorescence phantom, wherein the phantom would be used for calibration of the catheter providing accurate NIRAF values to the user using the sheath phantom to calibrate an optical probe's measured NIRAF signal to the known fluorescence of the phantom.

NIRAF calibration sheath phantom

An optical coherence tomography (OCT) system comprises: an imaging catheter; a calibration phantom removably arranged at least partially surrounding the distal end of the catheter; and a processor configured to control the catheter to acquire OCT images. The phantom has known dimensions and specific optical properties which provide non-changing calibration fiducials that span the imaging range of the system. The phantom is imaged by the catheter upon first connection to the system. The processor calculates a thickness of the phantom in the OCT image, and preforms z-offset calibration by setting the position of a phantom surface in the OCT image to a known nominal value. The known nominal value is related to one or more of the known thickness of the phantom or a diameter of the catheter sheath or a nominal angle of the light beam or the imaging range of the system.

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Cambridge, MA, United States of America

Christopher Douglas Brushett