Glaxo Group Limited

Glaxo Wellcome Inc.

Christopher David Bevan

Ian Martin Mutton

Derek Peter Reynolds

Alan Peter Hill

The present invention relates to an improved analytical method and apparatus therefor, in particular to a method and apparatus for continuous titration in which at least one parameter of at least one compound in a test mixture may be monitored as the composition of the mixture is continuously varied. The method comprises the steps of continuously mixing at least two component fluid streams to form a test mixture stream and passing the test mixture stream through a spectrophotometric detection zone, with the volume to volume ratio of at least two of the component streams forming the test mixture stream continuously and linearly varied with time by alteration of the relative proportions of the component streams forming the test mixture, while the total volume of the test mixture stream remains constant.

Analytical method and apparatus therefor involving continuous titration

The present invention relates to a method and apparatus for managing liquid flow through small bore tubing ( ) or channels ( ) by freezing the liquid or thawing the frozen liquid in a small segment of the tube or channel.

Liquid flow management means

The present invention relates to a method and apparatus for managing liquid flow through small bore tubing (1,2,3) or channels (13) by freezing the liquid or thawing the frozen liquid in a small segment of the tube or channel.

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Stevenage, United Kingdom

Christopher David Bevan