Snap-on Inc.

Snap-on Technologies, Inc.

Medimmune Limited

Snap-on Tools Corporation

Snap-on Tools Company

Medlmmune Limited

Christopher D Thompson

Daniel M Eggert

Joseph R Hoepfl

Alan Hunter

David T Ross

Michael Foster

Thomas Linke

Ambarish Shah

Hasige Sathish

William K Wang

Jeffrey H Hoff

Timothy Pabst

Xiangyang Wang

Frank Mikic

Gene E Olson

Richard L Hopper

Thomas F Foust

Jeffrey M Arendt

Jake Vail

Eric T Gustafson

Liu Tie

Mariko Fonseca

Yiming Li

Timm R Herman

Bert Krivec

Jonathan I Andersen

Marco E DeVecchis

Charles H Heiligenthal

David F Brekke

Anup A Gupte

Michael G Gentile

John J Landree

Gerald R Bakula

Michaela Wendeler

Robert A Cornog

Gerald L Socha

Mark J Knapp

Guoling Xi

Andrew Fulton

Michael D Schoenbeck

Jeffery H Hoff

Marco E Devecchis

Tools, for example, hexagon sockets, dodecagonal sockets, splined sockets, wrenches, etc., that have inner surface geometries adapted to engage a flank of a fastener at a point away from a corner of the fastener. This increases the strength and life of the socket, reduces a risk of the fastener becoming locked or stuck in the socket, and reduces the risk of the fastener being stripped or the socket slipping on the fastener.

Socket drive improvement

Sockets, for example, hexagon sockets, dodecagonal sockets, and splined sockets, that have inner surface geometries adapted to engage a flank of a fastener at a point away from a corner of the fastener. In general, the sockets engage the flank of the fastener at a distance of about 30 to 60 percent of half a length of the flank away from the corner of the fastener. This increases the strength and life of the socket, reduces a risk of the fastener becoming locked or stuck in the socket, and reduces the risk of the fastener being stripped or the socket slipping on the fastener.

A reversing lever with a compact structure is disclosed. The reversing lever can include an upper portion operable by a user to select a desired rotational direction of the tool, and a lower portion that selectively engages at pawl to choose the desired torque application. The body of the upper portion can be located between the internal wall of a ratchet head and a rear side of the lower portion of the lower portion to allow a compact reversing lever.

Reversing lever

Aqueous ozone hand sanitation device

Adjustable pliers includes a first plier half, a second plier half coupled to the first plier half, and a stud disposed in a slot of the second plier half. The first plier half includes a first handle and a first working tip opposite the first handle. The second plier half includes a second handle and second working tip opposite the second handle. The slot extends along a path from a first end of the path to a second end of the path, the path extends in a first direction at the first end of the path and extending in a second direction substantially parallel to the first direction at the second end of the path. A performance parameter is defined, at least in part, by a relationship between dimensions of the slot or of the second working tip.

Adjustable pliers

A pawl mechanism with a bias member that biases the pawl into engagement with the drive gear. The bias member can be a tube spring disposed within a bore to bias the pawl into engagement with the drive gear while eliminating the need for a spacer, as required by prior art ratchet wrenches.

Ratchet wrench with tube spring

Aqueous ozone generator cartridge

The present invention relates to a method of purifying albumin-fusion proteins to reduce the level of oxidation of susceptible amino acid residues. The method comprises an affinity matrix chromatography step and an anion exchange chromatography step. The purified albumin-fusion proteins have low levels of oxidation and retain their enhanced half-life in vivo and its bioactivity. In some embodiments, the albumin-fusion protein comprises a scaffold, such as human Tenascin C scaffold. Compositions comprising the albumin-fusion protein are further disclosed.

Method of purifying albumin-fusion proteins

A button lock that selectively retains the angle of an object relative to a handle. The button lock is rotatable between an engaged position, where the angle is retained, and a disengaged position, where the object is disengaged from the handle and can pivotally move about the handle to change the angle. In the engaged position, button teeth on the button engage with handle teeth on the handle. In the disengaged position, the button teeth disengage the handle teeth to space the button from the handle and therefore allow free movement of the handle about the button. The button therefore quickly and easily retains the angle between the object and the handle.

Flex joint lock button

A lift arm of a floor jack is composed of a number of components made from metal bar stock. The lift arm is adapted to transfer power and motion from a power unit to a saddle, which is adapted to be placed at a lift point of the vehicle, thereby applying pressure to the lift point and raising the vehicle.

Floor jack lift arm

The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.

Method for purifying active polypeptides or immunoconjugates

A ratcheting wrench with ratchet heads coupled to a handle via a pin. The pin includes two ball detents that couple to the teeth of the spline in and an indent inside an opening of the ratchet head. The wrench can therefore be easily used in low profile applications and quickly adjusted due to the dual ball detent configuration of the pin.

Ratcheting wrench

A tool that includes a wrench body a first drive end, and a ratchet gear disposed in an aperture in the first drive end. A first cavity is formed in the first drive end and in communication with the aperture. First and second pawls are disposed in the first cavity, and the first and second pawls each includes teeth adapted to engage the ratchet gear. A second cavity is formed in the first drive end and is in communication with the first cavity. The second cavity receives a reversing disc adapted to selectively engage the first and second pawls to cause engagement and dis-engagement of the first and second pawls with the ratchet gear. By orienting the pawls to allow the second cavity to have a minimum depth, the head of the wrench can be stiffened, thereby increasing fatigue strength and rigidity of the wrench.

Ratchet mechanism for ratchet wrench

Growing community of inventors

Franklin, WI, United States of America

Christopher D Thompson