Biomerieux, Inc.

Other

Christopher Cotter

Bruno Colin

Bryan W Kluttz

Geoff A McKinley

Michel Guy

Louis Graziano

Fabio Gennari

Luigi Catanzariti

Jacques Dachaud

Cecile Jaravel

Cecile Paris

Luigi Catazariti

Jacque Dachaud

James Clement Bishop

Garry R Tegeler

James K Greer

Lawrence Burg

C&eacute;cile Paris

Robert Glassfold

Michael Morin

Thomas Wang

An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature. A pneumatic system is also provided that assists in fluid transfer of a reaction solution from the first chamber to the second chamber.

Nucleic acid amplification reaction station for disposable test devices

A unit dose test device for a nucleic acid amplification reaction has the form of a elongate disposable test strip. The test strip includes a dual-chamber reaction vessel pre-loaded with nucleic acid amplification reaction reagents, and a plurality of wells for processing a reaction occurring in the reaction vessel.

Disposable test devices for performing nucleic acid amplification reactions

Growing community of inventors

Charlestown, MA, United States of America

Christopher Cotter