Creighton University

Streck, Inc.

Christopher Connelly

Matthew R Kreifels

Nancy D Hanson

Joel Lechner

Stacey Morrow

Stephanie Cossette

Laura R Porter

Cathy Scheer

Maria Torres-Gonzalez

Randy Fowler

Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.

Assays and methods for determining microbial resistance

Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple &#x3b2;-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of &#x3b2;-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.

Growing community of inventors

Gretna, NE, United States of America

Christopher Connelly