Koninklijke Philips Corporation N.V.

Christopher Anthony Procyk

Anandi Mahadevan

Mark Christopher McDermott

William Anthony Truschel

William A Truschel

Systems and method for determining zero subject flow rate for correcting leak estimation in respiratory devices. Estimating leak in respiratory devices is necessary for proper ventilation of the subject. Correctly estimating leak allows synchronous triggering and enables accurate measurements of respiratory parameters such as tidal volumes and peak flows to be performed. The systems () and the method () herein provide a solution to correct () for errors in leak estimation methods through analysis () of flow rate of the pressurized flow of breathable gas generated () by a pressure generator () of a respiratory device, and identification or estimation () of the flow rate of the pressurized flow at which zero subject flow rate occurs, wherein adjustments to the employed leak estimation method can be thereafter made. The analysis and determination or estimation involve clustering methods, in particular analysis of a histogram of flow rate parameter values determined for individual sampling intervals, wherein the flow rate parameter value corresponding to zero subject flow rate is determined on the basis of the histogram and may involve determining a histogram bin or range value having the highest number of flow rate parameter values or mode of the histogram.

Determining of subject zero flow using cluster analysis

Sleep apnea can be treated using positive airway pressure. Methods and systems for determining a level of airway obstruction allow beneficial adjustments to the level of expiratory positive airway pressure used to treat a subject.

Systems and methods for treating sleep apnea

A pressurized flow of breathable gas is delivered to the airway of a subject in accordance with a therapy regimen. The therapy regimen calls for maintenance of an average tidal volume. The therapy ensures that the subject breaths at a therapeutic breath rate. The breath rate may be determined dynamically based on breathing of the subject early on in a therapy session and/or based on a detected wakefulness of the subject. Inspiration for spontaneous and non-spontaneous breaths may be supported at different levels. The therapy regimen further maintains a beneficial positive end expiratory pressure, to reduce respiratory obstructions and/or for other purposes.

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New Kensington, PA, United States of America

Christopher Anthony Procyk