Pfizer Corporation

Christophe Philippe Allais

Joseph Walter Strohbach

David Hepworth

Stephen Wayne Wright

Frank Eldridge Lovering

Christoph Martin Dehnhardt

Eddine Saiah

John Paul Mathias

Christoph Wolfgang Zapf

Nikolaos Papaioannou

Arthur Lee

Dafydd Rhys Owen

Katherine Lin Lee

John David Trzupek

Seungil Han

Lori Krim Gavrin

Agustin Casimiro-Garcia

Chulho Choi

Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. 

Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Bicyclic-fused heteroaryl or aryl compounds as IRAK4 modulators

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. 

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Ledyard, CT, United States of America

Christophe Philippe Allais