Pall Life Sciences Belgium Bvba

Atmi Bvba

Pall Technology UK Limited

Pall Life Sciences Belgium

Christophe Braet

Steven Vanhamel

Tom Claes

José Castillo

Jean-Pascal Zambaux

Florence Bosco

Nicolas Havelange

A disposable material processing apparatus, useable as a bioreactor or fermenter, includes a hollow tank () and a mixing paddle () disposed within the interior of the tank and adapted to mix contents therein. The paddle may be isolated within a flexible sleeve (). Various functional elements, such as a sparger, sensor, material extraction conduit, material addition conduit, and/or heat exchange element may be provided, and optionally arranged to travel with the paddle within the tank interior. Baffles may protrude into a mixing tank to enhance mixing. A tank and/or sleeve may comprise polymeric film materials.

Disposable bioreactor

A system providing a sterile connection between a sensor probe and a fluid processing apparatus (e.g., a bioreactor) includes a first probe receiving element mountable to the fluid processing apparatus and a second probe receiving element having a gas-permeable contaminant barrier material and coupleable to the first probe receiving element. A sensor probe may be mounted to the second probe receiving element, with the combination being sterilized with a sterilant gas such as steam. Following such sterilization, connection between the first and second probe receiving elements is made through matable sterile couplings, and the probe is insertable through the coupled receiving elements to a position in fluid contact with the interior of the fluid processing apparatus.

Bioreactor probe connection system

Growing community of inventors

Muizen, Belgium

Christophe Braet