Myriad International Gmbh

Siemens Healthcare Diagnostics Gmbh

M2p-Labs Gmbh

Sividon Diagnostics Gmbh

Christoph Petry

Andreas Knorr

Karlheinz Hildenbrand

Guido Hennig

Mathias Gehrmann

Ralf Kronenwett

Christian Von Törne

Inke Sabine Feder

Karsten Weber

Mareike Dartmann

Werner Kroll

Detlef Schuppan

Kerstin Bohmann

Elmar-Reinhold Burchardt

Sylvia Unger

Michael J Arthur

Niklas Frische

Alastair D Burt

Massimo Pinzani

Robert P Thiel

Jan Brase

William Rosenberg

Stephan Schwers

Michael Volker

Michael Becka

Alexander Kremers

Elke Reifenberger

Guido Henning

The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient the RNA expression levels of at least 2 of the following 9 genes: UBE2C, BIRC5, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST, and MGP (b) mathematically combining expression level values for the genes of the said set which values were determined in the tumor sample to yield a combined score, wherein said combined score is indicative of a prognosis of said patient; and kits and systems for performing said method.

Method for breast cancer recurrence prediction under endocrine treatment

The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising:

The invention provides diagnostic methods, kits, and systems, and related computer-readable media, which use multiple blood marker values, including serum and plasma marker values, to aid in the diagnosis of the status or progress of a liver disease in a patient. The invention also provides methods and systems, and related computer-readable media, that use blood marker values, including serum and plasma marker values: (1) to screen for active ingredients useful in the treatment of a liver disease; (2) to aid in the selection of treatment regimens for patients that are predisposed to, or suffer from, liver disease; and (3) to aid in the design of clinical programs useful in monitoring the status or progress of liver disease in one or more patients.

Liver disease-related methods and systems

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Cologne, Germany

Christoph Petry