Brainlab Ag

Roche Diagnostics Operations, Inc.

Siemens Healthcare Gmbh

Christoph Pedain

Andreas Hartlep

Raghu Raghavan

Martin Lee Brady

Rainer Birkenbach

Achim Sinz

Stephan Mittermeyer

Maria Inmaculada Rodriguez Ponce

Philipp Tanner

Benedikt Krueger

Namitha Mallikarjunaiah

Shiva Ashish Thumparthy

Ricardo Daniel Carneiro Gomes

Andrea Hartlep

Florian Hager

Ilya Sher

Mike Keglovich

Zeev Glozman

A computer-implemented method provides a requested medical data record to a receiving entity. The method includes receiving a set of medical data records and receiving or initiating a joint data index and, for each medical data record of the set, applying a plurality of hash functions to a patient identifier corresponding to the medical data record to determine a hash vector, the patient identifier corresponding to the medical data record identifying the patient being subject of the medical data record, and updating the joint data index based on the hash vector. Furthermore, it includes providing the joint data index to the receiving entity and receiving a request for a record, corresponding to a request patient identifier and being based on the joint data index, from the receiving entity. The method includes providing the requested medical data record to the receiving entity via a secure communication channel.

Providing and receiving medical data records

Methods are disclosed for setting up a microservice, enhancing a ledger of microservices with a further microservice and accessing medical datasets stored in a microservice. The microservice contains the medical dataset in an encrypted form. The microservice includes an access logic based on accessing entity information. The access logic defines access conditions to the medical dataset and is configured to grant access to the medical dataset upon the access conditions being fulfilled.

Storing and accessing medical datasets on the blockchain

A method and a device for handling sample tubes are presented. A position of the sample tube is identified and the sample tube is handled depending thereon.

Method for handling a sample tube and handling device

A laboratory sample distribution system and a laboratory automation system comprising such a laboratory sample distribution system are presented. The laboratory sample distribution system comprises a number of sample container carriers adapted to move autonomously and to communicate with each other and with a central control unit.

Laboratory sample distribution system and laboratory automation system

A method of operating a laboratory automation system is presented. The laboratory automation system comprises a plurality of laboratory stations and a plurality of sample container carriers. The sample container carriers carry one or more sample containers. The sample containers comprise samples to be analyzed by the laboratory stations. The system also comprises a transport plane. The transport plane supports the sample container carriers. The system also comprises a drive. The drive moves the sample container carriers on the transport plane. The method comprises, during an initialization of the laboratory automation system, logically reserving at least one buffer area on the transport plane and, after the initialization of the laboratory automation system, buffering in the at least one buffer area sample container carriers carrying sample containers comprising samples waiting for a result of an analysis. Depending on the result of the analysis, the samples are further processed.

Method of operating a laboratory automation system and a laboratory automation system

A laboratory sample distribution system is presented. The system comprises sample container carriers carrying a sample container and comprising a magnetically active device. The system also comprises a transport plane supporting the sample container carriers and comprises drive modules comprising first line shaped conductors extending in a first direction and arranged parallel to each other and second line shaped conductors extending in a second direction and arranged parallel to each other. The system comprises a driver electrically connected to each of the first and second conductors of the drive modules. The driver selectively applies a drive current and/or voltage to the first and second conductors such that a conductor current results in the conductors driven by the drive current and/or voltage. The conductor current selectively causes a drive force to the sample container carriers such that the sample container carriers move along individual transport paths on the transport plane.

A system and method for treating Parkinson's disease by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region. Delivery of the agent can be coordinated with an applied electrical stimulation.

Targeted infusion of agents against parkinson's disease

A system and method for treating Alzheimer's disease by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region.

Targeted immunization and plaque destruction against Alzheimer's disease

A system and method for treating Amyotrophic Lateral Sclerosis (ALS) by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region.

Targeted infusion of agents for treatment of ALS

A method for planning an infusion into hepatic tissue into a patient includes: obtaining anatomical and/or physiological patient data of the patient's liver or a region of the liver; determining at least one patient parameter from the patient data; planning the infusion using the anatomical patient data, physiological patient data, and/or at least one patient parameter, wherein planning includes determining how an administered substance is distributed in the tissue and/or how the administered substance influences physiological properties of the tissue; and determining a distribution and/or effectiveness of a therapeutic agent administered with the substance or after the substance.

Method and device for planning a direct infusion into hepatic tissue

A medical tracking system includes a localization system operative to spatially localize medical instruments; a computer operative to assign absolute and/or relative positions of said instruments in a coordinate system; and at least one localizable gamma camera operative to detect gamma radiation emitted from a tracer material.

Medical tracking system using a gamma camera

A medical imaging processing method includes: using an imaging method to acquire at least first and second data sets of a region of interest of a patient's body, with at least one image acquisition parameter being changed so that first and second data sets yield different contrast levels relating to different substance and/or tissue types, and wherein the at least one acquisition parameter used to obtain the first data set is selected to enhance the contrast between one of the substance and/or tissue types relative to other substance and/or tissue types, and the at least one acquisition parameter used to obtain the second data set is selected to enhance the contrast between a different one of the substance and/or tissue types relative other substance and/or tissue types, thereby to optimize the contrast between at least three different substance and/or tissue types; and processing the two data sets to identify the different tissue types and/or boundaries therebetween.

Brain tissue classification

A method for planning to treat tissue by administering a substance which emits energy or can interact with administered energy to a body, such as body tissue, wherein a dispersion of the substance in the body is simulated, and to a system or device for planning administering a substance and administering energy to a body or in body tissue. The device includes a data capture unit configured to detect patient-specific parameters, wherein the patient-specific parameters can be used to describe a dispersion behavior of the substance in the body or body tissue; a computational unit operatively coupled to the data capture unit, said computational unit configured to obtain the patient-specific parameters from the data capture unit; a database accessible by the computational unit, wherein the database includes data for describing characteristics of a particular type of tissue or a particular body structure, data for describing mechanisms for supplying energy, and/or data for describing the effect on tissue of a substance in combination with supplied energy, the computational unit being configured to retrieve and/or store said data in the database; and an input unit via which a user can input treatment-specific data to the computational unit, wherein the computational unit is configured to simulate the plan based on at least one of the patient-specific data, data stored in the database, or user input data.

Method and device for assisting in a tissue treatment

A catheter having an outer profile which is formed such that a path length along an outer surface of the catheter is greater than the corresponding length of the catheter, and to a method for determining the shape of a catheter, and wherein the elasticity and/or conductivity of the tissue into which the catheter is to be introduced is taken into account in order to determine the outer profile of the catheter.

Intracranial catheter

The invention relates to a catheter stylet for stiffening a catheter during the placing process, wherein the stylet comprises an accommodating lumen for at least one fluid-guiding line of the catheter. It also relates to a catheter stylet catheter system, comprising such a stylet and comprising a catheter which comprises a fluid-guiding line, and to a method for stiffening a catheter during the placing process, wherein a stylet which comprises an accommodating lumen is arranged around at least one fluid-guiding line of the catheter.

Growing community of inventors

Munich, Germany

Christoph Pedain