Basf Aktiengesellschaft

Christoph Nubling

Wolfgang Siegel

Andreas Kramer

Frank Funke

Hartmut Riechers

Arthur Hohn

Joachim Simon

Karl-Otto Westphalen

Helmut Walter

Wolfgang Von Deyn

Uwe Kardorff

Matthias Gerber

Peter Plath

Stefan Engel

Wolfgang Ladner

Bernhard Hauer

Harald Rang

Hartmann Konig

Friedhelm Balkenhohl

Uwe Pressler

Jurgen Kast

Optically active amines are racemized by reaction of the optically active amine in the gas phase at elevated temperature in the presence of hydrogen and a hydrogenation or dehydrogenation catalyst.

Racemization of optically active amines

In a process for racemizing optically active amines by reacting the optically active amine in the presence of hydrogen and a hydrogenation or dehydrogenation catalyst at elevated temperature, the reaction is carried out in liquid phase and the catalyst comprises the catalytically active constituents copper, silver, iron, cobalt, nickel, ruthenium, rhodium, palladium, osmium, iridium and/or platinum and a support material selected from the group consisting of aluminum oxide, zirconium dioxide, titanium dioxide, carbon and/or oxygen compounds of silicon.

Racemizing of optically active amines

A process for the preparation of racemic amines of the formula I ##STR1## where R.sup.1 and R.sup.2 are different and R.sup.1, R.sup.2, R.sup.3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R.sup.3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III ##STR2## and the amine of the formula R.sup.3 NH.sub.2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.

Herbicidal pyrazine derivatives

Synthesis of optically active aminoindanol

Resolution of the racemates of primary and secondary amines by

Saccharin derivatives

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Hassloch, Germany

Christoph Nubling