Basf Se Corporation

Basf Aktiengesellschaft

Christoph Jäkel

Rocco Paciello

Gunnar Heydrich

Joachim Schmidt-Leithoff

Rainer Stürmer

Thomas Mackewitz

Nawid Kashani-Shirazi

Martin Volland

Bernhard Breit

Martine Weis

Marko Friedrich

Wolfgang Seiche

Christoph Waloch

Klaus Ebel

Wolfgang Krause

Matthias Rauls

Gabriele Gralla

Steffen Oehlenschläger

Peter Hofmann

Eike Johannes Bergner

Frank Hettche

Corina Scriban

Patrick Hanno-Igels

The present invention relates to a particularly economic overall method for producing menthol, specifically for producing optically active, essentially enantiomerically and diastereomerically pure L-menthol and racemic menthol, starting from the starting material citral which is available inexpensively on an industrial scale. The method has the following steps

Method for producing optically active, racemic menthol

A process for preparing optically active 2-methylalkan-1-ol of the general formula (III) comprising the following steps: 

Method for producing optically active 2-methyl-alkanols

The present invention relates to a continuous process for preparing neral (cis-citral) in pure or enriched form by distillatively separating neral from substance mixtures comprising essentially neral and geranial (trans-citral). This distillative separation is performed in a dividing wall column or in a connection of two distillation columns in the form of a thermal coupling.

Continuous process for preparing neral in pure or enriched form

The present invention relates to a process for preparing optically active carbonyl compounds by asymmetrically hydrogenating &#x3b1;,&#x3b2;-unsaturated carbonyl compounds in the presence of optically active transition metal catalysts which are soluble in the reaction mixture and have at least one carbon monoxide ligand, the optically active catalyst which has at least one carbon monoxide ligand and is to be used in each case being prepared by pretreating a catalyst precursor with a gas mixture comprising carbon monoxide and hydrogen and the asymmetric hydrogenation being performed in the presence of carbon monoxide supplied additionally to the reaction mixture.

Method for synthesizing optically active carbonyl compounds

Method for producing an optically active 2-methyl-alkane-1-ol from the corresponding 2-methylalk-2-en-1-al, comprising carbonyl-selective reduction, enantioselective hydration and lipase-catalyzed, stereoselective acylation in order to enrich the desired

The present invention relates to a process for asymmetric synthesis in the presence of a chiral catalyst comprising at least one complex of a metal of transition group VIII with ligands capable of dimerization via noncovalent bonds, such catalysts and their use.

Method for asymmetric synthesis

The invention relates to a process for preparing optically active alkylsuccinic acid monoalkyl esters of the formula (I) where D and E are independently of one another H, C-Calkyl, R is C-Calkyl, aryl or alkylaryl.

Method for the production of optically active alkyl succinic acid monoalkyl esters

The present invention relates to a process for preparing optically active carbonyl compounds by asymmetrically hydrogenating &#x3b1;,&#x3b2;-unsaturated carbonyl compounds in the presence of optically active transition metal catalysts which are soluble in the reaction mixture and have at least one carbon monoxide ligand. The present invention especially relates to a process for preparing optically active aldehydes or ketones, in particular citronellal, by asymmetrically hydrogenating the corresponding optically active &#x3b1;,&#x3b2;-unsaturated aldehydes or ketones.

Method for the production of optically active carbonyl

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Limburgerhof, Germany

Christoph Jäkel