Universitätsklinikum Freiburg

Oxira Medical Inc.

Hehrlein, Christoph, Dr.

Christoph Hehrlein

Todd F Davenport

Michael Braun

John S Geis

Gerhard Karl Wolf

Adalbert Kovacs

A device for detaching parietal thrombi from a bodily vessel is described having a catheter including at least one catheter section with a catheter wall with at least one wall opening which passes completely through the catheter wall. The catheter wall along the least one catheter section is made of a resiliently deformable material in which the at least one wall opening includes a separating helical gap wound around the catheter wall at least in parts along the catheter section. A fixing device permits releasable fixing of the catheter on a bodily vessel so that the catheter can be converted, exclusively by an external mechanical constraint in the form of a torque acting torsionally on the catheter, from a state of smaller catheter outer diameter to a state of larger catheter outer diameter.

Device for detaching parietal thrombi from a blood vessel

A device for detaching parietal thrombi from a blood vessel is disclosed, comprising a catheter including at least one catheter section, wherein an outer diameter of the at least one catheter section is changeable and at least one wall opening extends transversely through a wall of the at least one catheter section. The catheter wall along the at least one catheter section is a resilient and deformable material. The catheter is transformed from a smaller catheter outer diameter to a uniform larger catheter outer diameter by a resilient change in shape. A displacement body can be introduced into the at least one catheter section which is transformed in diameter to deform the catheter from the smaller catheter outer diameter to the larger outer diameter for capturing thrombus material.

A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.

Method and apparatus for delivering oxygen and/or other gases to tissue

The invention described herein consists of an oxygen deliver source for local blood or tissue oxygenation. The invention consists of porous polymer structures being part of a medical device from which a liquid oxygen carrier is locally or systemically released. The substrate membrane impregnated with the oxygen carrier may be a part of a tube, a balloon, a perfusion balloon, a stent and a wire. The substrate membrane is sealed with a removable housing for the oxygen carrier to allow storage of the medical device.

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Freiburg, Germany

Christoph Hehrlein