Dibra S.p.a.

Bracco Imaging S.p.a.

Christoph De Haen

Fulvio Uggeri

Luigia Gozzini

Luciano Lattuada

Pier Lucio Anelli

Marino Brocchetta

Pierfrancesco Morosini

Monica Muttoni

Ornella Gazzotti

Julius P Zodda

Ernst Felder

Massimo Visigalli

Enrico Cappelletti

Marcella Murru

Franco Fedeli

Mario Virtuani

Michael N Eakins

Giovanna Lux

Andrea Beltrami

Giuseppe Manfredi

Michele Serleti

Daniela Palano

Angelo Gallotti

Anne Marie Smith

Valtero Canepa

Lorenzo Morelli

Vittorio Bottazzi

Compounds able to chelate paramagnetic metal ions and the use thereof as contrast agents in the technique known as &ldquo;Magnetic Resonance Imaging&rdquo; (M.R.I.).

Bile acids conjugates with metal ion chelates and the use thereof

Blood pool imaging contrast agents containing paramagnetic bi- and tri-valent metal ion chelates of bile acid conjugates with molecules having chelating activity are used in magnetic resonance imaging of the vascular system and particularly the coronaries.

Use of bile acid conjugates, derivatives thereof with metal complexes as blood pool agents for nuclear magnetic resonance diagnostics

Devices, and a method for the use thereof, for the standardization of signal intensity in the formation of magnetic resonance images of the human body, said devices including one or more straight, bent or flexible closed tubes with an external diameter not greater than 3 cm, an internal diameter of not less than 0.2 cm and a length of not less than 8 cm, made of susbtantially diamagnetic material, other than glass, preferably a plastic material, particularly polyvinyl chloride, each of them being filled with aqueous solutions or gels containing paramagnetic components, said tubes being kept close to the body either by means of the positioning devices of the body to which they are fixed permanently or temporarily, or by fixings which, on one side, can be fixed to the human body and on the other keep the tubes in the required positior.

Device for the standardization of signal intensity in the magnetic

Pharmaceutical and diet formulations for the prophylaxis and treatment

Branched, dendrimeric macromolecules having a central nucleus and a series of polyoxaalkylene chains that radiate from the nucleus and spread into the surrounding space branching a cascade fashion until the desired size results. Molecules formed in this manner are free of excessive functional crowding on their outer surfaces. Synthetic methods of preparing these molecules and their uses are described.

Binary-branched polyoxaalkylene macromolecules process for making them

Container for diagnostic contrast compositions

The present invention concerns Lactobacillus strains and pharmaceutical compositions containing them.

Lactobacillus strains of human origin, their compositons and uses thereof

The present invention concerns the use of dendrimeric-type branched macromolecules, comprising polyoxaalkylene chains, as catalysts or coadjuvants of phase transfer catalysis reactions.

Use of dendrimeric-type macromolecules as catalysts or coadjuvants in

Aqueous injectable formulations useful for radiodiagnosis comprising

Iodinated paramagnetic chelates, and their use as contrast agents

Novel paramagnetic metal ion chelates and their use as contrast agents in the diagnostic technique known as 'magnetic resonance imaging' (M.R.I.) of the gastrointestinal tract and particularly of the liver, are described. The novel compounds result from the conjugation of a bile acid with a chelating agent and are capable of chelating the ions of bivalent and trivalent metals. The compounds have formula A-L-B in which A is the residue of a bile acid and derivatives of a bile acid, B is the residue of a chelating agent of a bivalent or trivalent metal ion having an atomic number of 20 to 31, 39, 42, 43, 44, 49, 57 to 83, L is a ligand between A and B.

Paramagnetic metal icon chelates and use thereof as contrast agents in

Tetraiodopyrrole derivatives as contrast medium and as antiseptic

A process for the production of prefilled syringes free from dangerous residual air or gas bubbles, in short production times.

Process for the preparation of prefilled syringes without residual gas

Growing community of inventors

Milan, Italy

Christoph De Haen