Jenavalve Technology Gmbh

Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Friedrich-schiller-universitaet Jena

Friedrich-schiller-universitat Jena

Jenavalve Technologies, Inc.

Leica Microsystems Lithography Gmbh

Leica Microststems Lithography Gmbh

Occlutech Gmbh

Christoph Damm

Hans-Reiner Figulla

Markus Ferrari

Johannes Jung

Helmut Straubinger

Thomas Peschel

Volker Guyenot

Stefan Risse

Robert Moszner

Rüdiger Ottma

Hans Reiner Figulla

Friedrich Moszner

Nicolas Lange

Erik Beckert

Carsten Weber

Andreas Gebhardt

Sebastian Scheiding

Claudia Bruchmann

Gerhard Kalkowski

Thomas Elster

Gerd Harnisch

Ulf-Carsten Kirschstein

Gerhard Schubert

Hans-Joachim Doering

Christoph Schenk

Susann Klebon

Thomas Töllner

Sylvia Gebhardt

Peggy Dörrer

Ralf Steinkopf

Michael Litzenburger

Claudia Reinlein

Marcel Hornaff

Thomas Burkhardt

Michael Scheiding

Andreas Kamm

Britta Satzer

Johannes Hartung

Matthias Mohaupt

Klaus Lang

Matthias Beier

Mathias Rohde

Christian Siebenhaar

The invention relates to a catheter for the transvascular implantation of prosthetic heart valves, in particular including self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation. To achieve this, according to the invention a prosthetic heart valve with anchorage supports is temporarily housed in a folded form in a cartridge-type unit (4) during the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system (1), which includes a flexible region (9) that can be guided through the aorta. Actuating elements (2, 3) run through the interior of the hollow guide system, said elements permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released.

Catheter system for implantation of prosthetic heart valves

A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.

Medical device for treating a heart valve insufficiency

A method and a device for producing an optical component having at least three monolithically arranged optical functional surfaces and an optical component are disclosed. The method includes calculating a continuous surface composite, which includes the first optical functional surface and the second optical functional surface, producing the continuous surface composite, which contains the first and second optical functional surfaces in a defined shape and a relative position to one another, on the first side of the optical component through machining by a machine tool, producing at least one reference surface arranged outside the optical functional surfaces on the optical component or on a mount and having a defined positional relation to the optical functional surfaces through machining by the machine tool and repositioning the optical component in such a way that the second side of the optical component is machined with the machine tool, wherein the at least one reference surface serves as a contact surface or mounting surface.

Method and device for producing an optical component having at least three monolithically arranged optical functional surfaces and optical component

A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent () with a prosthetic heart valve () at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve () can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis () in the patient's ventricle, the device includes a self-expanding positioning stent () introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent () so that the two stents respectively interact in their expanded states such that the heart valve stent () is held by the positioning stent () in a position in the patient's aorta relative the heart valve predefinable by the positioning stent ().

Device for the implantation and fixation of prosthetic valves

A catheter is described for the transvascular implantation of prosthetic heart valves, e.g., including self-expanding anchorage supports, to reduce the risk to the patient during the implantation. Accordingly, a prosthetic heart valve with anchorage supports is temporarily housed in a folded form in a cartridge-type unit during the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system, which includes a flexible region that can be guided through the aorta. Actuating elements run through the interior of the hollow guide system, permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released.

Medical device for treating a heart valve insufficency

The invention relates to an operating handle (--) for manipulating a catheter tip (--) of a catheter delivery system. The operating handle (--) comprises a hand grip () designed to be held by a user, and a manipulating part () axially aligned with the hand grip (). The manipulating part () is rotatable relatively to the hand grip () about a longitudinal axis (L) defined by the operating handle (--). The operating handle (--) comprises at least one sliding member () operatively linked with the manipulating part () by means of a cam mechanism () such that, upon rotation of the manipulating part () relative to the hand grip (), the at least one sliding member () moves axially in the direction of the longitudinal axis (L).

Catheter delivery system for heart valve prosthesis

The invention relates to a catheter for the transvasculur implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation. To achieve this, according to the invention a prosthetic heart valve comprising anchorage supports is temporarily housed in a folded form in a cartridge-type unit () riming the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system (), which comprises a flexible region () that can be guided through the aorta. Actuating elements () run through the interior of the hollow guide system, said elements permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released.

Systems for implanting an endoprosthesis

Methods of implanting an endoprosthesis

The invention relates to a method for manufacturing a light weight optical mirror or a monolithic mirror comprising at least one cooling channel, the method comprising forming a mirror body by iteratively depositing a metallic powder in layers and applying, for each of the layers, heat at least in a subarea of this layer, thereby fusing or sintering the powder in this subarea and bonding it to a previously deposited layer, the powder remaining in an unfused state in at least one region, the method further comprising forming at least one cavity within the carrier by removing the unfused powder from said region and producing a mirror surface at a closed surface of the mirror body. The invention further relates to an optical mirror and to an optical device.

Method for manufacturing a mirror comprising at least one cavity and optical mirror

A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.

Growing community of inventors

Jena, Germany

Christoph Damm