Nanogen Recognomics Gmbh

Evonik Operations Gmbh

Windhab, Norbert

Brücher, Christoph

Christoph Brücher

Norbert Windhab

Markus Schweitzer

Stefan Raddatz

Richard R Anderson

Andreas Karau

Kevin Burton

Stefan Kienle

Andrea Engel

Julia Lyubina

Michael D Fiechtner

Daguang Wang

Charles Greef

Thomas J Onofrey

John R Havens

Peter Niepoth

Paul Joseph Spencer

Jessica Müller-Albers

Jochen Müller-Ibeler

Jochen Müller

Jill M Orwick

Eberhard Schneider

Marc Pignot

Carsten Dentler

Rüdiger Alexowsky

Jill Orwick

Richard Anderson

A method of unambiguous identification and authentication of products for the purpose of better recognition of product forgeries and controlling product piracy, including applying to/into the product an identification substance admixture which contains paramagnetic phases or identifying a product which contains an identification substance admixture containing paramagnetic phases and has an ESR fingerprint spectrum that permits unambiguous identification of the product. Such an ESR fingerprint spectrum is easily measurable, but can be copied or forged only with difficulty. The method relates to an individualizable 'femto tag' for femto ledgers and forms an important interface for what are known as “Internet of Things” (IOT).

Unique identification and authentication of products

This invention relates to attachment chemistries for binding macromolecules to a substrate surface or to other conjugation targets. More particularly, this invention relates to attachment chemistries involving branched or linear structures having one or more hydrazide attachment moieties for binding the macromolecules to a substrate surface, or for other conjugation reactions. Novel modifying reagents are provided for the introduction of protected hydrazide attachment moieties or precursor forms of such hydrazides to the macromolecule, either as a single hydrazide or as multiple hydrazides.

Hydrazide building blocks and hydrazide modified biomolecules

The present invention relates to conjugates of synthetic binding units and nucleic acids. The present invention also relates to methods for sorting and immobilizing nucleic acids on support materials using such conjugates by specific molecular addressing of the nucleic acids mediated by the synthetic binding systems. Particularly, the present invention also relates to novel methods of utilizing conjugates of synthetic binding units and nucleic acids to in active electronic array systems to produce novel array constructs from the conjugates, and the use of such constructs in various nucleic acid assay formats. In addition, the present invention relates to various novel forms of such conjugates, improved methods of making solid phase synthesized conjugates, and improved methods of conjugating pre-synthesized synthetic binding units and nucleic acids. The present invention also relates to the use of conjugates of synthetic binding units and nucleic acids as substrates for various enzymatic reactions, including nucleic acid amplification reactions.

Enzymatic modification of a nucleic acid-synthetic binding unit conjugate

Growing community of inventors

Eschborn, Germany

Christoph Brücher