Astrazeneca Ab

Depuy Synthes Products, Inc.

Christine K Ward

Lorin Roskos

Bing Wang

Donald Raible

Anna Gosiewska

Anthony J Kihm

David C Colter

Compositions and methods of using cells derived from umbilical cord tissue to stimulate and support lung tissue angiogenesis, to improve blood flow to lung tissue, to regenerate, repair, and improve lung tissue damaged by lung disease, disorder and/or injury, and to protect lung tissue from damage caused by lung disease, disorder and/or injury in a patient.

Treatment of lung and pulmonary diseases and disorders

Provided herein are methods of improving asthma symptoms, e.g., as measured by an asthma control questionnaire, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.

Methods for improving asthma symptoms using benralizumab

Provided herein is are methods of increasing forced expiratory volume in one second (FEV) in an asthma patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.

Methods for increasing forced expiratory volume in asthmatics using benralizumab

Provided herein is are methods of reducing exacerbations of asthma in an asthma patient, comprising administering to the patient an effective amount of the anti-interleukin-5 receptor (IL-5R) antibody benralizumab or an antigen-binding fragment thereof.

Growing community of inventors

Gaithersburg, MD, United States of America

Christine K Ward